冬眠花栗鼠心肌中的兴奋-收缩偶联
Excitation-contraction coupling in the myocardium of hibernating chipmunks.
作者信息
Kondo N
出版信息
Experientia. 1986 Dec 1;42(11-12):1220-2. doi: 10.1007/BF01946394.
PMID:3780943
Abstract
In the myocardium of nonhibernating chipmunks, replacing external Ca by Sr markedly prolongs the action potential plateau with an increase in contraction, while in preparations from hibernating animals this procedure inhibits both responses. Pretreatment with 4-aminopyridine causes a prolongation of the action potential plateau by Sr in hibernating animals.
摘要
在非冬眠花栗鼠的心肌中，用锶替代细胞外钙可显著延长动作电位平台期，并增强收缩作用，而在冬眠动物的组织标本中，此操作会抑制这两种反应。用4-氨基吡啶预处理可使冬眠动物的锶延长动作电位平台期。
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