Grover Jagrit, Maji Suman, Teja Chitrala, Al Thabaiti Shaeel A, Mostafa Mohamed Mokhtar M, Lahiri Goutam K, Maiti Debabrata
Department of Chemistry, IIT Bombay, Powai, Mumbai 400076, India.
K. A. CARE Energy Research and Innovation Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia, Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
ACS Org Inorg Au. 2023 Jul 24;3(5):299-304. doi: 10.1021/acsorginorgau.3c00023. eCollection 2023 Oct 4.
We herein report a novel Mn-SNS-based catalyst, which is capable of performing indirect hydrogenation of CO to methanol formylation. In this domain of CO hydrogenation, pincer ligands have shown a clear predominance. Our catalyst is based on the SNS-type tridentate ligand, which is quite stable and cheap as compared to the pincer type ligands. The catalyst can also be recycled effectively after the formylation reaction without any significant change in efficiency. Various amines including both primary and secondary amines worked well under the protocol to provide the desired formylated product in good yields. The formed formylated amines can also be reduced further at higher pressures of hydrogen. As a whole, we have developed a protocol that involves indirect CO hydrogenation to methanol that proceeds formylation of amines.
我们在此报告一种新型的基于Mn-SNS的催化剂，它能够将CO间接氢化为甲醇进行甲酰化反应。在CO加氢这个领域，钳形配体已显示出明显的优势。我们的催化剂基于SNS型三齿配体，与钳形配体相比，它相当稳定且便宜。该催化剂在甲酰化反应后也能有效回收，且效率没有任何显著变化。包括伯胺和仲胺在内的各种胺在该方案下都能很好地反应，以良好的产率提供所需的甲酰化产物。在更高的氢气压力下，生成的甲酰化胺也可以进一步还原。总体而言，我们开发了一种涉及将CO间接氢化为甲醇以进行胺的甲酰化反应的方案。
