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[因静脉压升高导致经血管的液体向脑内移动]

[Transvascular fluid movement into the brain in response to an increase in venous pressure].

作者信息

Krasil'nikov V G, Artem'eva A I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Sep;72(9):1180-8.

PMID:3781046
Abstract

An increase in pressure of the venous outflow under conditions of perfusion with constant blood flow of hemodynamically isolated brain, led to filtration of fluid from the cerebral vascular bed in anesthetized cats. Velocity of the transvascular translocation of fluid was proportional to the pressure increase by 50, 75 and 100 mm Hg in cerebral veins. The capillary filtration coefficient (CFC) was about 0.11-0.12 ml/100 g of tissue/mm Hg/min. Reasons for a relatively great CFC found in the brain, are discussed.

摘要

在对血流动力学孤立的大脑进行恒流灌注的情况下,静脉流出压力增加,导致麻醉猫的脑血管床出现液体滤过。在脑静脉压力升高50、75和100毫米汞柱时,液体跨血管转运的速度与压力升高成正比。毛细血管滤过系数(CFC)约为0.11 - 0.12毫升/100克组织/毫米汞柱/分钟。文中讨论了在大脑中发现相对较高CFC的原因。

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