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[以不同方式灌注的工作骨骼肌中跨毛细血管液体交换的特征]

[Characteristics of transcapillary fluid exchange in working skeletal muscles perfused in various ways].

作者信息

Makovskaia V A, Savel'ev A K, Dvoretskiĭ D P, Tkachenko B I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Mar;72(3):368-72.

PMID:3709866
Abstract

Acute experiments in cats revealed by means of volumometry of extracorporeal blood flow that the exchange surface of the microcirculation bed in working skeletal muscles increased irrespective of whether they were perfused under constant pressure or in constant blood flow. Capillary hydrostatic pressure depended on the perfusion mode: it decreased in conditions of stabilized blood expenditure through muscles, and increased in constant pressure perfusion. An increase of the capillary filtration coefficient is considered from the standpoint of dilatory effect of metabolites on precapillary sphincters. Changes of pre-and postcapillary resistance take part in shifts of fluid movement in the muscle during contraction.

摘要

在猫身上进行的急性实验通过体外血流容积测定法显示,无论工作中的骨骼肌是在恒压下灌注还是在恒定血流下灌注,其微循环床的交换面积都会增加。毛细血管静水压取决于灌注方式:在肌肉稳定供血的情况下它会降低,而在恒压灌注时会升高。从代谢产物对毛细血管前括约肌的扩张作用角度来考虑毛细血管滤过系数的增加。毛细血管前和后阻力的变化参与了肌肉收缩期间液体流动的改变。

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