Fargeas Christine A, Jászai József, Corbeil Denis
Tissue Engineering Laboratories, Biotechnology Center (BIOTEC) Center for Molecular and Cellular Bioengineering and Medizinische Fakultät der Technischen Universität Dresden Dresden Germany.
Institute of Anatomy Medizinische Fakultät der Technischen Universität Dresden Dresden Germany.
Reprod Med Biol. 2023 Oct 4;22(1):e12544. doi: 10.1002/rmb2.12544. eCollection 2023 Jan-Dec.
The contribution of Prominin-1 (aka CD133) to male fertility has recently been (re)investigated, with contradictory results. Early findings, essential for deciphering its role, have unfortunately been neglected. Here, the authors present what is currently known about its expression in the male reproductive system of rodents and men so that its involvement in male fertility can be re-examined and discussed in the light of these elements.
Prominin-1（又称CD133）对男性生育能力的作用最近已被（重新）研究，但结果相互矛盾。不幸的是，对于解读其作用至关重要的早期研究结果被忽视了。在此，作者介绍了目前已知的其在啮齿动物和人类男性生殖系统中的表达情况，以便根据这些因素重新审视和讨论其在男性生育能力中的作用。
