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原发性醛固酮增多症导致严重低钾血症引起的致死性心律失常:病例报告及文献复习。

Lethal Arrhythmia Induced by Severe Hypokalemia with Primary Aldosteronism: A Case Report and Literature Review.

机构信息

Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Japan.

出版信息

Intern Med. 2024 May 15;63(10):1405-1413. doi: 10.2169/internalmedicine.1931-23. Epub 2023 Oct 6.

Abstract

A 26-year-old woman experienced sudden loss of consciousness with respiratory arrest while engaged in a heated conversation shortly after consuming a carbohydrate-rich meal; she was resuscitated immediately. Severe hypokalemia became evident and was deemed to have caused lethal arrhythmia. She was diagnosed with a left aldosterone-producing adenoma and achieved remission following partial adrenalectomy. Primary aldosteronism is frequently complicated by hypokalemia; however, hypokalemia-induced lethal arrhythmias are rare. Clinicians should recognize that primary aldosteronism can potentially cause sudden death in apparently healthy individuals; hence, an early diagnosis and proper treatment are critical.

摘要

一位 26 岁女性在进食富含碳水化合物的餐后不久与人激烈交谈时突然失去意识并伴有呼吸停止,立即进行了抢救。严重低钾血症明显,被认为导致了致命性心律失常。她被诊断为左侧醛固酮分泌腺瘤,部分肾上腺切除术使病情得到缓解。原发性醛固酮增多症常伴有低钾血症;然而,低钾血症引起的致命性心律失常较为罕见。临床医生应认识到原发性醛固酮增多症可导致看似健康的个体发生猝死;因此,早期诊断和适当的治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3724/11157302/9ae309732cef/1349-7235-63-1405-g001.jpg

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