Chen Yun, Lyu Xiangpei, Li Tao, Wang Huanqiang
National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
China CDC Wkly. 2023 Sep 22;5(38):844-848. doi: 10.46234/ccdcw2023.160.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: The application of whole lung lavage (WLL) for the clinical treatment of pneumoconiosis is prevalent in China. Several scholars have reported success in the treatment of early-stage pneumoconiosis. Nonetheless, the overall efficacy of WLL in the management of pneumoconiosis remains ambiguous.
WHAT IS ADDED BY THIS REPORT?: The preliminary evaluation of the effects of WLL on pneumoconiosis patients was conducted using follow-up data from 2020 to 2022, after controlling for confounding factors via propensity score matching. While the study found that WLL may improve some pneumoconiosis symptoms, no significant enhancements were observed in overall health status or quality of life.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: The findings of this research indicate limited efficacy of WLL in treating patients with pneumoconiosis, thereby suggesting that it should not be utilized as a standard treatment procedure for this condition.
关于该主题已知的信息有哪些？：全肺灌洗（WLL）在中国用于尘肺病的临床治疗很普遍。几位学者报告了早期尘肺病治疗的成功案例。尽管如此，WLL在尘肺病治疗中的总体疗效仍不明确。
本报告补充了哪些内容？：在通过倾向得分匹配控制混杂因素后，利用2020年至2022年的随访数据对WLL对尘肺病患者的影响进行了初步评估。虽然研究发现WLL可能改善一些尘肺病症状，但在总体健康状况或生活质量方面未观察到显著改善。
对公共卫生实践有哪些启示？：本研究结果表明WLL在治疗尘肺病患者方面疗效有限，因此表明它不应被用作该疾病的标准治疗程序。
