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既往有一次剖宫产史后子宫破裂的预测因素:一项非匹配病例对照研究。

Predictors of Uterine Rupture After One Previous Cesarean Section: An Unmatched Case-Control Study.

作者信息

Arusi Temesgen Tantu, Zewdu Assefa Dereje, Gutulo Muluken Gunta, Gensa Geta Teshome

机构信息

Department of Obstetrics and Gynecology, Wolkite University College of Health Science, Wolkite, Ethiopia.

Department of Obstetrics and Gynecology, Hawassa University, Hawassa City, Ethiopia.

出版信息

Int J Womens Health. 2023 Oct 4;15:1491-1500. doi: 10.2147/IJWH.S427749. eCollection 2023.

Abstract

BACKGROUND

Uterine rupture is a rare occurrence but has catastrophic complications during pregnancy. The incidence is relatively higher in scarred uteri because there is a promotion of labor after cesarean section. There is a scarcity of evidence from low-income countries regarding the predictors of uterine rupture after trial labor.

OBJECTIVE

To assess factors determining uterine rupture during labor after the previous cesarean section among mothers delivered at Hawassa University Comprehensive Specialized Hospital from September 2017 to September 2022.

METHODS

A facility-based unmatched case-control study was done by reviewing 105 patients, which included 35 cases and 70 controls in a 1:2 case-to-control ratio. The association between dependent and independent variables was sought with running binary and multivariate analyses by using the cut point of a p value < 0.05 and 95% CI.

RESULTS

The prevalence of uterine rupture is 1.6%. The factors significantly associated with uterine rupture after trial of labor are fetal weight >3.8 kg (AOR: 5.21), antenatal care 4 (AOR: 3.6), labor duration >15 hours (AOR: 10.7), and previous successful vaginal delivery (AOR: 3.4). Poor fetal-maternal outcomes like 91.4% fetal death, 29 hysterectomies, 22 blood transfusions, and 1 death.

CONCLUSION

The prevalence is relatively higher than in developed countries. The number of antenatal care, labor duration, and lower fetal weight are not common findings associated with uterine rupture after trial of labor across the literature, so large-scale studies are needed to develop guidelines for the Ethiopian setup. Improving the quality of obstetrics care given in each level of health system.

摘要

背景

子宫破裂虽属罕见,但在孕期会引发灾难性并发症。剖宫产术后促进分娩,瘢痕子宫的子宫破裂发生率相对较高。低收入国家关于试产后子宫破裂预测因素的证据匮乏。

目的

评估2017年9月至2022年9月在哈瓦萨大学综合专科医院分娩的经剖宫产的母亲试产期间子宫破裂的决定因素。

方法

通过回顾105例患者进行了一项基于机构的非匹配病例对照研究,病例与对照比例为1:2,包括35例病例和70例对照。通过二元和多变量分析寻找因变量和自变量之间的关联,使用p值<0.05和95%置信区间的切点。

结果

子宫破裂的患病率为1.6%。试产后与子宫破裂显著相关的因素为胎儿体重>3.8千克(调整后比值比:5.21)、产前检查4次(调整后比值比:3.6)、产程>15小时(调整后比值比:10.7)以及既往有成功阴道分娩史(调整后比值比:3.4)。出现了不良的母婴结局,如91.4%的胎儿死亡、29例子宫切除术、22例输血以及1例死亡。

结论

患病率相对高于发达国家。产前检查次数、产程以及较低的胎儿体重并非文献中试产后子宫破裂常见的相关发现,因此需要开展大规模研究以制定埃塞俄比亚的相关指南。提高卫生系统各层级提供的产科护理质量。

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本文引用的文献

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Prediction of vaginal birth after cesarean deliveries using machine learning.采用机器学习预测剖宫产术后阴道分娩。
Am J Obstet Gynecol. 2020 Jun;222(6):613.e1-613.e12. doi: 10.1016/j.ajog.2019.12.267. Epub 2020 Jan 30.
5
[Influencing factors and antenatal assessment of the vaginal birth after cesarean section].[剖宫产术后阴道分娩的影响因素及产前评估]
Zhonghua Fu Chan Ke Za Zhi. 2019 Jun 25;54(6):369-374. doi: 10.3760/cma.j.issn.0529-567x.2019.06.003.
8
Risk factors for complete uterine rupture.子宫完全破裂的危险因素。
Am J Obstet Gynecol. 2017 Feb;216(2):165.e1-165.e8. doi: 10.1016/j.ajog.2016.10.017. Epub 2016 Oct 22.
10
[Clinical study on vaginal birth after cesarean].剖宫产术后阴道分娩的临床研究
Zhonghua Fu Chan Ke Za Zhi. 2016 Aug 25;51(8):586-91. doi: 10.3760/cma.j.issn.0529-567X.2016.08.007.

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