应激对绵羊钙稳态的影响。

Effect of stress on calcium homeostasis in sheep.

作者信息

Balabanova S, Hartmann J, Töllner U, Nowak R, Kirkpatrick U C

出版信息

Horm Res. 1986;24(4):302-6. doi: 10.1159/000180571.

Abstract

The acute effect of stress on the plasma and cerebrospinal fluid (CSF) immunoreactive parathyroid hormone (PTH) response was studied in 6 merino sheep. Stress was exerted by weak periodical electric square waves (PESW). In addition, the effect of intravenous injection of adrenaline was studied. Under stress conditions (PESW or adrenaline injection), plasma PTH increased up to 30% and up to 50%, respectively. Weak periodical electric square waves of 3-4 mA decreased CSF PTH concentrations by up to 50%. The effect of adrenaline injection on the CSF PTH was not significant. Total calcium and magnesium in plasma and CSF did not change. Our results showed that the effect of stress on the CSF PTH is opposite to the effect on plasma PTH, and suggest that both, PESW and adrenaline, affected PTH in plasma and CSF by a Ca-independent mechanism.

摘要

在6只美利奴绵羊中研究了应激对血浆和脑脊液（CSF）免疫反应性甲状旁腺激素（PTH）反应的急性影响。应激通过弱周期性电方波（PESW）施加。此外，还研究了静脉注射肾上腺素的影响。在应激条件下（PESW或肾上腺素注射），血浆PTH分别升高高达30%和50%。3-4 mA的弱周期性电方波使脑脊液PTH浓度降低高达50%。肾上腺素注射对脑脊液PTH的影响不显著。血浆和脑脊液中的总钙和镁没有变化。我们的结果表明，应激对脑脊液PTH的影响与对血浆PTH的影响相反，并表明PESW和肾上腺素均通过钙非依赖机制影响血浆和脑脊液中的PTH。