Zhang C, Liao H, Li H, Xu Y, Zhang G, Wang X, Bao H
Department of Anesthesiology, Nanjing Hospital Affiliated to Nanjing Medical University/ Nanjing First Hospital, Nanjing 210006, China.
Department of Anesthesiology, Affiliated Brain Hospital of Nanjing Medical University, Nanjing 210029, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2023 Sep 20;43(9):1599-1605. doi: 10.12122/j.issn.1673-4254.2023.09.18.
To explore the effect of THRIVE combined with i-gel laryngeal mask on the safety of oxygen therapy in apnea and surgical precision of retrograde intrarenal surgery.
A total of 120 patients undergoing retrograde intrarenal surgery under general anesthesia with laryngeal mask were randomized into 3 groups (=40), and after the flexible ureteroscope entered the renal pelvis and located the stones, the patients received assisted ventilation in APPV mode (control group), ventilation with small tidal volume and high respiratory rate (group H), or THRIVE combined with laryngeal mask for oxygen supply without using the ventilator (THRIVE group). The time for lithotripsy by the surgeons, surgeons' satisfaction, diaphragm mobility, and times of urinary tract mucosal injury were recorded, and arterial blood pressure, heart rate, SpO, PaO, PaCO, and pH value were measured before, during and after lithotripsy.
Among the 3 groups, THRIVE group had the shortest time for lithotripsy, best satisfaction of the surgeons, the lowest diaphragmatic mobility of the patients, and the smallest number of mucosal injuries. The arterial blood pressure, heart rate, and SpO of the patients did not differ significantly among the 3 groups. At 20 min and 30 min after the start of lithotripsy, PaO decreased significantly in group H and THRIVE group; in THRIVE group, PaCO increased and pH decreased significantly at 10, 20 and 30 min after the start of lithotripsy. No significant difference was found in oxygenation indicators among the 3 groups upon discharge from the PACU.
In retrograde intrarenal surgery, THRIVE combined with i- gel laryngeal mask for oxygen therapy during the anaerobic period can improve the surgical accuracy and maintain the patient's oxygenation index in a controllable range within 30 min.
探讨THRIVE联合i-gel喉罩对呼吸暂停患者氧疗安全性及逆行性肾内手术手术精度的影响。
选取120例行喉罩全身麻醉下逆行性肾内手术的患者,随机分为3组(每组 =40)。在软性输尿管镜进入肾盂并定位结石后,患者分别接受APPV模式辅助通气(对照组)、小潮气量高呼吸频率通气(H组)或THRIVE联合喉罩供氧且不使用呼吸机(THRIVE组)。记录外科医生碎石时间、外科医生满意度、膈肌活动度及尿路黏膜损伤次数,并在碎石前、碎石期间和碎石后测量动脉血压、心率、SpO、PaO、PaCO及pH值。
3组中,THRIVE组碎石时间最短,外科医生满意度最高,患者膈肌活动度最低,黏膜损伤数量最少。3组患者的动脉血压、心率及SpO差异无统计学意义。碎石开始后20分钟和30分钟时,H组和THRIVE组PaO显著下降;THRIVE组在碎石开始后10分钟、20分钟和30分钟时PaCO升高且pH显著下降。从PACU出院时,3组的氧合指标差异无统计学意义。
在逆行性肾内手术中,THRIVE联合i-gel喉罩在无氧期进行氧疗可提高手术精度,并在30分钟内将患者氧合指数维持在可控范围内。