Unit of Otorhinolaryngology - Head and Neck Surgery, ASST Spedali Civili of Brescia, Brescia, Italy.
Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, School of Medicine, Brescia, Italy.
Acta Otorhinolaryngol Ital. 2023 Dec;43(6):382-389. doi: 10.14639/0392-100X-N2623. Epub 2023 Oct 10.
The aim of the present study is to describe our novel surgical technique of hemicricoidectomy and reconstruction with modified rotational thyro-crico-tracheal anastomosis for the treatment of non-squamous cell subglottic tumours. The procedure has been defined as Type E crico-tracheal resection and anastomosis (CTRA) following the University of Brescia (C)TRA classification introduced elsewhere.
A detailed anatomical step-by-step dissection was reproduced and illustrated on a cadaveric laryngo-tracheal specimen. Moreover, oncological and functional outcomes of the first 5 patients who underwent Type E CTRA at our Institution between October 2016 and September 2022 are described.
Three patients underwent Type E CTRA for cricoid chondrosarcoma (CS) and 2 patients for subglottic adenoid cystic carcinoma (ACC). No post-operative complication was reported. All patients maintained intact oral intake and an intelligible voice at discharge. All but one patient with obstructive sleep apnoea hypopnea syndrome and lung comorbidity were successfully decannulated before discharge. At the last follow-up (April 2023), one patient experienced local recurrence of CS that was still amenable to conservative treatment by transoral debulking, while the remaining patients were free of disease.
With the proper indications, Type E CTRA is a feasible and effective conservative surgical technique for selected non-squamous cell subglottic tumours.
本研究旨在描述我们治疗非鳞状细胞声门下肿瘤的新型半环切除术和改良旋转甲状软骨-气管吻合术的重建方法。该手术已根据布雷斯西亚大学(C)TRA 分类(其他地方介绍)定义为 E 型环状软骨-气管切除术和吻合术(CTRA)。
在尸体喉气管标本上重复并详细描述了解剖学的分步说明。此外,还描述了 2016 年 10 月至 2022 年 9 月期间在我院接受 E 型 CTRA 的前 5 例患者的肿瘤学和功能结果。
3 例患者因环状软骨软骨肉瘤(CS)接受 E 型 CTRA,2 例患者因声门下腺样囊性癌(ACC)接受 E 型 CTRA。无术后并发症。所有患者出院时均保持完整的经口摄入和可理解的声音。所有除 1 例阻塞性睡眠呼吸暂停低通气综合征和肺部合并症的患者在出院前均成功拔管。在最近的随访(2023 年 4 月)中,1 例 CS 局部复发的患者仍可通过经口减瘤术进行保守治疗,而其余患者均无疾病。
在适当的适应证下,E 型 CTRA 是一种可行且有效的保守性手术技术,适用于特定的非鳞状细胞声门下肿瘤。