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腹腔镜辅助残胃癌根治术与腹腔镜全胃切除术的短期和中期结果比较。

Laparoscopic Completion Total Gastrectomy for Remnant Gastric Cancer Compared to Laparoscopic Total Gastrectomy in Short- and Medium-Term Results.

机构信息

Division of Surgery Shamir Medical Center Affiliated with University Tel Aviv, Zerefin, Israel.

出版信息

J Laparoendosc Adv Surg Tech A. 2023 Nov;33(11):1047-1051. doi: 10.1089/lap.2023.0241. Epub 2023 Oct 9.

DOI:10.1089/lap.2023.0241
PMID:37815593
Abstract

The incidence of remnant gastric cancer is increasing in recent years. The advantages of minimally invasive surgery for gastric cancer are well established. However, laparoscopic completion total gastrectomy for remnant gastric cancer harbors difficulties due to adhesions, changed configuration of the anatomical organs, and changes on the lymphatic flow. We aim to investigate the feasibility, safety, and the short-term outcomes of laparoscopic completion total gastrectomy compared to laparoscopic total gastrectomy. All patients who underwent total gastrectomy from January 2018 to December 2021 at Shamir Medical Center were included in the study. Patients were divided into two groups-completion gastrectomy and total gastrectomy. The groups were compared for demographics, operative, and clinical outcomes. Overall, 22 patients were included in the study. Eight were completion gastrectomy following subtotal gastrectomy for malignancy and 14 were primary total gastrectomy. All operations were performed by minimal invasive surgery technique. Average age was 64 years, with no differences in gender. Two major intraoperative complications were noted in completion group (25% versus 0%,  = .12). Both length of surgery (3:03 versus 3:40,  = .049) and length of stay (7 days versus 9 days,  = .5) were shorter in completion group. There were fewer postoperative complications (12.5% versus 28.5%,  = .61). Average number of harvested lymph nodes was significantly lower in completion group (10 versus 33,  = .002). Laparoscopic completion total gastrectomy for remnant gastric cancer is safe and feasible having comparable oncological surrogate's parameters and recurrence profile. Clinical Registration Number: 0015-22-ASF.

摘要

近年来,残胃癌的发病率呈上升趋势。微创外科治疗胃癌的优势已得到充分证实。然而,由于粘连、解剖器官结构改变和淋巴液流动改变,腹腔镜完成性全胃切除术治疗残胃癌存在困难。我们旨在探讨与腹腔镜全胃切除术相比,腹腔镜完成性全胃切除术的可行性、安全性和短期结果。

所有在 2018 年 1 月至 2021 年 12 月期间在沙米尔医疗中心接受全胃切除术的患者均纳入本研究。患者分为两组:完成性胃切除术和全胃切除术。对两组患者的人口统计学、手术和临床结果进行比较。

总体而言,本研究共纳入 22 例患者。其中 8 例为恶性肿瘤行次全胃切除术后的完成性胃切除术,14 例为原发性全胃切除术。所有手术均采用微创外科技术进行。平均年龄为 64 岁,性别无差异。完成组有 2 例术中严重并发症(25%比 0%, = .12)。手术时间(3:03 比 3:40, = .049)和住院时间(7 天比 9 天, = .5)均较短。术后并发症较少(12.5%比 28.5%, = .61)。完成组的淋巴结清扫数目明显较少(10 比 33, = .002)。

腹腔镜完成性全胃切除术治疗残胃癌安全可行,具有可比较的肿瘤替代参数和复发特征。

临床注册号

0015-22-ASF。

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