Bhutani V, Kumar V, Misra U K
Int J Vitam Nutr Res. 1986;56(3):275-9.
Effect of feeding rice diets with and without lysine and threonine supplementation has been studied on phospholipid turnover of rat pancreas and compared to rats fed casein diet at 20% protein level. Rice diet without amino acid supplementation significantly reduced the levels of pancreas PC, PE, PI, PS and Sph and increased that of total cholesterol and TG. Incorporation of palmitate-1-14C, labelled choline, labelled methionine and NaH2(32)PO4 into PC and of palmitate-1-14C into TG was significantly reduced in rats fed unsupplemented rice diet. Incorporation of NaH2(32)PO4 into pancreas PI, DPI, TPI, PA, LPA and into IP, IP2', IP3 and GPI was significantly reduced in rats fed unsupplemented rice diet.
研究了补充和未补充赖氨酸及苏氨酸的大米日粮对大鼠胰腺磷脂周转的影响,并与饲喂蛋白质水平为20%的酪蛋白日粮的大鼠进行了比较。未补充氨基酸的大米日粮显著降低了胰腺中磷脂酰胆碱(PC)、磷脂酰乙醇胺(PE)、磷脂酰肌醇(PI)、磷脂酰丝氨酸(PS)和鞘磷脂(Sph)的水平,并提高了总胆固醇和甘油三酯(TG)的水平。在饲喂未补充氨基酸大米日粮的大鼠中,棕榈酸-1-14C、标记胆碱、标记蛋氨酸和NaH2(32)PO4掺入PC以及棕榈酸-1-14C掺入TG的量显著降低。在饲喂未补充氨基酸大米日粮的大鼠中,NaH2(32)PO4掺入胰腺PI、二磷脂酰肌醇(DPI)、三磷脂酰肌醇(TPI)、磷脂酸(PA)、溶血磷脂酸(LPA)以及肌醇磷酸(IP)、IP2'、IP3和糖基磷脂酰肌醇(GPI)的量显著降低。