Department of Oncology,PuerPeople's Hospital,China.
Department of Oncology,Puer People's Hospital,China.
J Pak Med Assoc. 2023 Sep;73(9):1862-1868. doi: 10.47391/JPMA.6830.
Precision medicine will be the direction of future medical development, especially in cancer diagnosis and treatment. With the deepening of breast cancer-related research, new factors related to diagnosis, treatment and prognosis are constantly being discovered. Researchers combine different factorsto form a multigene panel testing, guiding clinicians' decision-making. The application scope of multigene panel detection is constantly expanding. At present, it has been tried in the prognosis evaluation of lymph node-positive and human epidermal growth factor receptor 2-positive breast cancer patients and the early screening of breast cancer. With continuous technological advancement, there will be broader application prospects in the future. The current narrative review was planned to evaluate the recent advances in applying multigene panel testing in breast cancer cases.
精准医学将是未来医学发展的方向，尤其在癌症的诊断和治疗方面。随着乳腺癌相关研究的深入，新的与诊断、治疗和预后相关的因素不断被发现。研究者们将不同的因素结合起来形成多基因panel 检测，指导临床医生进行决策。多基因 panel 检测的应用范围不断扩大，目前已经尝试应用于淋巴结阳性和人表皮生长因子受体 2 阳性乳腺癌患者的预后评估和乳腺癌的早期筛查中。随着技术的不断进步，未来将会有更广阔的应用前景。本综述旨在评估多基因 panel 检测在乳腺癌中的应用进展。
