Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India.
Pharm Nanotechnol. 2024;12(4):314-328. doi: 10.2174/0122117385265554230919070402.
Epilepsy is a serious neurological disease, and scientists have a significant challenge in developing a noninvasive treatment for the treatment of epilepsy. The goal is to provide novel ideas for improving existing and future anti-epileptic medications. The injection of nano treatment via the nose to the brain is being considered as a possible seizure control method. Various nasal medicine nanoformulations have the potential to cure epilepsy. Investigations with a variety of nose-to-brain dosing methods for epilepsy treatment have yielded promising results. After examining global literature on nanotechnology and studies, the authors propose nasal administration with nanoformulations as a means to successfully treat epilepsy. The goal of this review is to look at the innovative application of nanomedicine for epilepsy treatment via nose-to-brain transfer, with a focus on the use of nanoparticles for load medicines. When nanotechnology is combined with the nose to brain approach, treatment efficacy can be improved through site specific delivery. Furthermore, this technique of administration decreases adverse effects and patient noncompliance encountered with more traditional procedures.
癫痫是一种严重的神经疾病,科学家们在开发非侵入性治疗癫痫的方法上面临着重大挑战。目标是为改进现有和未来的抗癫痫药物提供新的思路。通过鼻腔向大脑注射纳米治疗被认为是一种可能的控制癫痫发作的方法。各种鼻用药物纳米制剂具有治疗癫痫的潜力。对各种用于治疗癫痫的鼻腔给药方法的研究取得了有希望的结果。作者在对纳米技术和研究的全球文献进行审查后,提出了用纳米制剂经鼻腔给药作为成功治疗癫痫的方法。本综述的目的是探讨通过鼻腔向大脑传递的纳米医学在癫痫治疗中的创新应用,重点是使用纳米颗粒作为载药。当纳米技术与鼻腔向大脑的方法相结合时,通过特定部位的给药可以提高治疗效果。此外,这种给药技术可以减少传统方法中遇到的不良反应和患者不依从性。