对有望用于甾体修饰的子囊菌sp. VKM F-3040进行转录组组装。
transcriptome assembly of sp. VKM F-3040, a promising steroid-modifying ascomycete.
作者信息
Kollerov Vyacheslav V, Tarlachkov Sergey V, Donova Marina V
机构信息
G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Federal Research Center "Pushchino Center for Biological Research" of Russian Academy of Sciences Prospekt Nauki , Pushchino, Moscow region, Russia.
出版信息
Microbiol Resour Announc. 2023 Nov 16;12(11):e0066323. doi: 10.1128/MRA.00663-23. Epub 2023 Oct 11.
Abstract
This research presents transcriptome shotgun assembly for sp. VKM F-3040, which is a putative fungal strain able to modify androstane steroids with production of 7-hydroxy and 17-hydroxylated derivatives-key intermediates in the synthesis of pharmaceutical ingredients. The data are of importance for creating novel microbial biocatalysts.
摘要
本研究展示了对菌株VKM F-3040的转录组鸟枪法测序组装结果，该菌株被认为是一种能够修饰雄甾烷类固醇并产生7-羟基和17-羟基化衍生物的真菌菌株，这些衍生物是药物成分合成中的关键中间体。这些数据对于创建新型微生物生物催化剂具有重要意义。
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