University of Waterloo, Department of Biology, Waterloo, Canada.
Canadian Rivers Institute Faculty of Forestry and Environmental Management, University of New Brunswick, Fredericton, NB, Canada.
Vet Immunol Immunopathol. 2023 Oct;264:110660. doi: 10.1016/j.vetimm.2023.110660. Epub 2023 Oct 6.
Telemetry tags are a widely used technology for tracking animals that are difficult to observe in their natural environment. This technology has been increasingly used to monitor and study populations of high value salmonid species in Canadian waters. This study expands on a previous study of the impacts of tag implantation on the immune system of Rainbow Trout (Oncorhynchus mykiss). Pro-inflammatory cytokines and protein level markers were examined in fish that underwent peritoneal implantation of three tag types and compared to a sham surgery control group. The different materials on the surface of the tags showed differential immune induction extending over a two-month period. This included peritoneal total protein, IL-1β protein, the immunoglobulins IgT and IgM, as well as pro-inflammatory transcripts in the spleen. These results are suggestive of a prolonged, costly foreign body response which may be differentially induced by the different types of tag coating, with ceramic tags being least immunogenic. Examining tag impacts at the level of the immune system will facilitate the development of more biocompatible tags which will improve data fidelity. This will support more effective strategies for the management of fisheries resources.
遥测标签是一种广泛用于跟踪在自然环境中难以观察到的动物的技术。这项技术已越来越多地用于监测和研究加拿大水域中高价值鲑鱼种群。本研究扩展了先前对虹鳟鱼（Oncorhynchus mykiss）免疫 系统中标签植入影响的研究。检查了三种标签类型进行腹膜内植入的鱼类中的促炎细胞因子和蛋白质水平标志物，并与假手术对照组进行了比较。标签表面的不同材料在两个月的时间内表现出不同的免疫诱导。这包括腹膜总蛋白、IL-1β 蛋白、免疫球蛋白 IgT 和 IgM 以及脾脏中的促炎转录物。这些结果表明存在一种延长的、代价高昂的异物反应，这可能是由不同类型的标签涂层引起的，其中陶瓷标签的免疫原性最低。在免疫系统水平上检查标签的影响将有助于开发更具生物相容性的标签，从而提高数据保真度。这将支持渔业资源管理的更有效战略。
