Yale University School of Medicine, Department of Psychiatry, New Haven, CT, United States of America; State University of Montes Claros (UNIMONTES), Graduate Program of Health Sciences, Montes Claros, MG, Brazil.
Centro Universitário FIPMOC (UNIFIPMOC), School of Medicine, Montes Claros, MG, Brazil.
Neurosci Lett. 2023 Nov 20;817:137511. doi: 10.1016/j.neulet.2023.137511. Epub 2023 Oct 12.
This crossover study explored the acute effect of a session of high-intensity interval training (HIIT) or moderate-intensity continuous training (MICT) on middle cerebral artery (MCA) variables such as cerebral blood velocity, pulsatility index (PI) and resistivity index (RI) through transcranial Doppler (TCD), and cognitive function (CF - verbal fluency and Digit Span) in healthy young adults. Participants (26 healthy young adults, 13 women, 24 ± 3 years) underwent two different randomized exercise sessions: (1) MICT (60 % heart rate reserve, HRR) and (2) HIIT (80 % HRR). MCA velocity, PI, RI, CF, and serum lactate were measured immediately before and after the sessions. HIIT demonstrated improved executive function/semantic fluency (20 %, p = 0.019), while both MICT and HIIT increased lactate (625 %, HIIT, p < 0.001, and 238 %, MICT, p < 0.001). Other assessments remained stable, except for reduced PI (p = 0.029) and RI (p = 0.023) after MICT, with no significant difference (pre-post for HIIT-MICT). Notably, cognition improvement correlated with lactate increase in HIIT (ρ = 0.436; p < 0.001). Executive function/semantic fluency increased after HIIT relative to MICT. The findings show that there are no systematic out-of-normal changes in the cerebrovascular circulation of clinically healthy adults undergoing HIIT and MICT.
这项交叉研究通过经颅多普勒（TCD）探讨了高强度间歇训练（HIIT）或中等强度持续训练（MICT）对健康年轻成年人大脑中动脉（MCA）变量（如脑血流速度、搏动指数（PI）和阻力指数（RI））和认知功能（CF-言语流畅性和数字跨度）的急性影响。参与者（26 名健康年轻成年人，13 名女性，24±3 岁）接受了两种不同的随机运动训练：（1）MICT（60%心率储备，HRR）和（2）HIIT（80% HRR）。MCA 速度、PI、RI、CF 和血清乳酸在训练前后立即测量。HIIT 显示执行功能/语义流畅性提高（20%，p=0.019），而 MICT 和 HIIT 均增加了乳酸（HIIT 增加 625%，p<0.001，MICT 增加 238%，p<0.001）。其他评估保持稳定，除了 MICT 后 PI（p=0.029）和 RI（p=0.023）降低，HIIT-MICT 之间没有显著差异（前后）。值得注意的是，HIIT 中认知改善与乳酸增加呈正相关（ρ=0.436；p<0.001）。HIIT 后执行功能/语义流畅性增加。研究结果表明，在接受 HIIT 和 MICT 的临床健康成年人中，脑血管循环没有出现系统性的异常变化。
