EPIUnit-Instituto de Saúde Pública, Universidade do Porto, 4050-600 Porto, Portugal.
Northern Region Health Administration, 4000-477 Porto, Portugal.
Int J Environ Res Public Health. 2019 Oct 28;16(21):4163. doi: 10.3390/ijerph16214163.
This study aimed to compare the acute effects of high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) on glycemic control in middle-aged and older patients with type 2 diabetes (T2D), using treadmill walking as aerobic exercise mode.
Fifteen patients with T2D (60.25 ± 3.14 years; glycated hemoglobin 7.03 ± 0.33%; medicated with metformin and/or gliptins), participated in a randomized controlled crossover trial. They underwent three experimental conditions (treadmill walking HIIT session (5 × (3 min at 70% of heart rate reserve (HRR) + 3 min at 30% HRR)); treadmill walking MICT session (30 min at 50% HRR); and a control session of rest (CON)) in random order and in the postprandial state. Measurements of capillary blood glucose (BG) were taken immediately before, during, and until 50 min after the experimental conditions.
Both HIIT and MICT treadmill walking sessions reduced BG levels during exercise and laboratory 50 min recovery period compared to CON (time*condition interaction effect; < 0.001). The effect of HIIT was greater compared with MICT ( = 0.017).
Treadmill walking HIIT seems a safe and more effective exercise strategy on immediate acute glycemic control compared with MICT in middle-aged and older patients with T2D under therapy with metformin and/or gliptins.
ISRCTN09240628.
本研究旨在比较高强度间歇训练（HIIT）与中等强度持续训练（MICT）对使用跑步机行走作为有氧运动模式的 2 型糖尿病（T2D）中老年患者血糖控制的急性影响。
15 名 T2D 患者（60.25±3.14 岁；糖化血红蛋白 7.03±0.33%；服用二甲双胍和/或格列汀）参与了一项随机对照交叉试验。他们接受了三种实验条件（跑步机行走 HIIT 组（5×（70%心率储备（HRR）下 3 分钟+30% HRR 下 3 分钟）；跑步机行走 MICT 组（50% HRR 下 30 分钟）；和休息对照条件（CON）），以随机顺序进行，并在餐后状态下进行。在实验条件前、期间和 50 分钟后测量毛细血管血糖（BG）。
与 CON 相比，HIIT 和 MICT 跑步机行走组在运动中和实验室 50 分钟恢复期内均降低了 BG 水平（时间*条件交互效应；<0.001）。与 MICT 相比，HIIT 的效果更大（=0.017）。
与 MICT 相比，在接受二甲双胍和/或格列汀治疗的中老年 T2D 患者中，跑步机行走 HIIT 似乎是一种安全且更有效的即时急性血糖控制的运动策略。
ISRCTN09240628。
