两种邻氨基苯甲酸酯类化合物在实验室条件下对热带臭虫（半翅目：臭虫科）的驱避效果。

Repellent effect of two anthranilates against the tropical bed bug Cimex hemipterus (Hemiptera: Cimicidae) demonstrated in laboratory assays.

机构信息

National Key Laboratory of Green Pesticide, Department of Entomology, South China Agricultural University, Guangzhou, China.

Department of Entomology, Rutgers University, New Brunswick, New Jersey, USA.

出版信息

Pest Manag Sci. 2024 Mar;80(3):988-995. doi: 10.1002/ps.7829. Epub 2023 Oct 26.

DOI:10.1002/ps.7829

PMID:37822111

Abstract

BACKGROUND

The bites and blood sucking of bed bugs (Cimex spp.) (Hemiptera: Cimicidae) pose a serious threat to human physical and mental health. Application of an effective repellent can prevent or reduce bed bug bites. Previous studies on repellent screening mainly focused on Cimex lectularius L. In this study, we investigated the repellent effect of two safe food additives, ethyl anthranilate (EA) and butyl anthranilate (BA), against Cimex hemipterus (F.), and also explored the role of antennae and mouthparts on C. hemipterus perception of repellents.

RESULTS

Both EA and BA had a strong repellent effect against tropical bed bugs and their repellency was similar or lower than that of N,N-diethyl-3-methyl benzoyl amide, depending on whether or not a CO source was present. EA had higher repellency than BA and exhibited repellency to C. hemipterus for 3 days when a CO source was present. C. hemipterus avoided resting on 20% EA- and BA-treated harborages. Applying 20% EA and BA on rabbit skin significantly reduced the blood intake of C. hemipterus within 2 h. C. hemipterus could perceive EA and BA after their antennae or mouthparts or both antennae and mouthparts were removed.

CONCLUSION

Both EA and BA had strong repellency against C. hemipterus, with EA being more repellent. Ablation of antennae and mouthparts did not affect the perception of EA and BA by C. hemipterus. © 2023 Society of Chemical Industry.

摘要

背景

臭虫（Cimex spp.）（半翅目：臭虫科）的叮咬和吸血对人类身心健康构成严重威胁。使用有效的驱避剂可以预防或减少臭虫叮咬。以前的驱避剂筛选研究主要集中在 Cimex lectularius L. 上。在这项研究中，我们调查了两种安全食品添加剂乙基邻氨基苯甲酸酯（EA）和丁基邻氨基苯甲酸酯（BA）对半翅目臭虫（Cimex hemipterus）的驱避效果，并探索了触角和口器在半翅目臭虫对驱避剂的感知中的作用。

结果

EA 和 BA 对热带臭虫均具有较强的驱避作用，其驱避效果与 N,N-二乙基-3-甲基苯甲酰胺相似或略低，这取决于是否存在 CO 源。当存在 CO 源时，EA 的驱避率高于 BA，且对 C. hemipterus 的驱避作用可持续 3 天。C. hemipterus 避免在 20% EA 和 BA 处理过的栖息地中栖息。在兔皮上涂抹 20% EA 和 BA 可显著减少 C. hemipterus 在 2 小时内的吸血量。切除触角和口器或同时切除触角和口器后，C. hemipterus 仍能感知 EA 和 BA。