氟暴露与血压之间的关联。
Association between fluoride exposure and blood pressure.
作者信息
Hung Man, Mohajeri Amir, Vu Teresa, Moparthi Hyma, Lipsky Martin S
机构信息
College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT, USA.
Division of Public Health, University of Utah, Salt Lake City, UT, USA.
出版信息
J Public Health Res. 2023 Oct 8;12(4):22799036231204323. doi: 10.1177/22799036231204323. eCollection 2023 Oct.
OBJECTIVES
This study investigated whether fluoride was associated with an increased prevalence of high blood pressure (BP) among adolescents in the United States.
METHODS
The study sample consisted of 2015-2016 National Health and Nutrition Examination Survey participants aged 13-17 years. Independent-samples tests, Chi-square tests, and regression models were used to analyze the data.
RESULTS
A total of 814 participants met the study criteria. The findings showed that the proportion of patients with high levels of water or plasma fluoride in the high BP group was higher than that in the normal BP group. However, after adjusting for sociodemographic covariates, neither water nor plasma fluoride levels were significantly associated with a high BP.
CONCLUSIONS
This study did not find an association between either water or plasma fluoride levels and high BP. Further study is needed to exclude a dose dependent effect at higher levels of fluoride.
目的
本研究调查了美国青少年中氟化物是否与高血压（BP）患病率增加有关。
方法
研究样本包括2015 - 2016年国家健康与营养检查调查中13 - 17岁的参与者。使用独立样本检验、卡方检验和回归模型分析数据。
结果
共有814名参与者符合研究标准。研究结果表明，高血压组中高水平水氟或血浆氟患者的比例高于正常血压组。然而，在调整社会人口统计学协变量后，水氟和血浆氟水平均与高血压无显著关联。
结论
本研究未发现水氟或血浆氟水平与高血压之间存在关联。需要进一步研究以排除更高氟水平下的剂量依赖性效应。
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