排尿生物力学的尿动力学磁共振成像研究的技术可行性：一项初步研究。
Technical feasibility of uro-dynamic MRI study of voiding biomechanics: a pilot study.
作者信息
Gonzalez-Pereira Juan Pablo, Johnson Cody John, Wells Shane, Bushman Wade, Roldan-Alzate Alejandro
机构信息
Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, USA.
Department of Radiology, University of Wisconsin-Madison, Madison, USA.
出版信息
Int Urol Nephrol. 2024 Mar;56(3):893-899. doi: 10.1007/s11255-023-03823-7. Epub 2023 Oct 12.
INTRODUCTION
Dynamic volumetric MRI was used to non-invasively assess voiding biomechanics in a healthy male volunteer.
METHODS
Using 3D Differential Subsampling with Cartesian Ordering (DISCO) Flex acquisition sequence, volumetric bladder images were obtained throughout the voiding effort. These were subsequently segmented using MIMICS. Segmented anatomical volumes were used to quantify total voided volume, post-void residual, volumetric displacement of urine over time, bladder neck angle, sphericity index, and prostatic urethral angle through the voiding effort.
RESULTS
Bladder sphericity index correlated positively with flow rate. The greatest degree of bladder neck funneling correlated with the maximum urine flow rate. There was straightening of the prostatic urethral angle during voiding that also correlated positively with urine flow.
CONCLUSION
This pilot study confirms the potential of dynamic MRI to provide non-invasive assessment of lower urinary tract anatomy and biomechanics during voiding.
引言
采用动态容积磁共振成像（MRI）对一名健康男性志愿者的排尿生物力学进行无创评估。
方法
使用笛卡尔排序的三维差分采样（DISCO）Flex采集序列，在整个排尿过程中获取膀胱容积图像。随后使用MIMICS对这些图像进行分割。分割后的解剖容积用于量化整个排尿过程中的总排尿量、排尿后残余尿量、尿液随时间的容积位移、膀胱颈角度、球形指数和前列腺尿道角度。
结果
膀胱球形指数与流速呈正相关。膀胱颈漏斗化程度最大时与最大尿流率相关。排尿过程中前列腺尿道角度变直，这也与尿流呈正相关。
结论
这项初步研究证实了动态MRI在排尿期间对下尿路解剖结构和生物力学进行无创评估的潜力。
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