Adelaide Medical School, The University of Adelaide, Adelaide Health and Medical Sciences Building, North Terrace, Adelaide, SA, 5000, Australia.
Robinson Research Institute, The University of Adelaide, Adelaide, Australia.
Matern Child Health J. 2023 Dec;27(12):2185-2193. doi: 10.1007/s10995-023-03778-2. Epub 2023 Oct 12.
Evaluate the association between poor mental health and risk of developing gestational diabetes mellitus (GDM) in a cohort of women from a socioeconomically disadvantaged community.
A total of 1363 nulliparous women with singleton pregnancies recruited to the Screening Tests to Predict Poor Outcomes of Pregnancy study in Adelaide, Australia. Women were assessed for mental health in the first trimester, including likelihood of depression, high functioning anxiety, perceived stress and risk of developing a mental health disorder. GDM was diagnosed based on the International Association of Diabetes in Pregnancy Study Group (IADPSG) criteria. Socioeconomic status was measured using the New Zealand Socioeconomic Index (NZSEI).
Complete mental health data was available for 1281 participants. There was no statistically significant difference in SEI, depression, risk of mental health issues, high functioning anxiety and perceived stress between women who developed GDM and those who did not. There was no difference in history of depression nor risk of developing a high mental health disorder in first trimester after adjusting for SEI, BMI in first trimester, smoking status in first trimester and maternal age between women with a GDM pregnancy and those who did not.
There was no difference in markers of poor mental health in early pregnancy between women who subsequently did or did not develop GDM. Cohort participants were socioeconomically disadvantaged, potentially contributing to the lack of apparent differences in depression observed between groups. Socioeconomically disadvantaged women should be targeted in pre-conception planning to reduce risk of GDM.
评估在一个社会经济处于不利地位的社区的女性队列中，心理健康状况不佳与发生妊娠期糖尿病（GDM）风险之间的关联。
共有 1363 名来自澳大利亚阿德莱德的 Screening Tests to Predict Poor Outcomes of Pregnancy 研究的初产妇参与了这项研究。在妊娠早期，女性接受了心理健康评估，包括抑郁、高功能焦虑、感知压力和发展精神障碍的风险。GDM 的诊断基于国际妊娠糖尿病研究组（IADPSG）标准。社会经济地位采用新西兰社会经济指数（NZSEI）衡量。
1281 名参与者的完整心理健康数据可用。在 SEI、抑郁、精神健康问题风险、高功能焦虑和感知压力方面，患有 GDM 和未患有 GDM 的女性之间没有统计学上的显著差异。在调整了 SEI、孕早期 BMI、孕早期吸烟状况和母亲年龄后，患有 GDM 妊娠的女性与未患有 GDM 的女性在孕早期的抑郁史或发展为高精神障碍的风险方面没有差异。
在 GDM 后发展或不发展 GDM 的女性中，在孕早期的不良心理健康标志物方面没有差异。队列参与者处于社会经济劣势地位，这可能导致观察到的两组之间的抑郁差异不明显。应在孕前计划中针对社会经济处于不利地位的妇女，以降低 GDM 的风险。
