Nagasawa Hiroki, Omori Kazuhiko, Muramatsu Ken-Ichi, Takeuchi Ikuto, Ohsaka Hiromichi, Ishikawa Kouhei, Yanagawa Youichi
Department of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University, 1129 Nagaoka, Izunokuni City, Shizuoka, 410-2295, Japan.
Int J Emerg Med. 2023 Oct 12;16(1):70. doi: 10.1186/s12245-023-00550-9.
Traumatic cardiac arrest (TCA) is associated with poor outcomes. Helicopter emergency medical services (HEMSs) are often used to transport critically ill patients to hospitals. However, the role of HEMS in the treatment of TCA remains unclear. Therefore, in this study, we aimed to determine the current status of patients with prehospital TCA managed by HEMS personnel in Japan and compare the outcomes of patients who experienced TCA before and after the arrival of HEMS.
The Japanese Society for Aeromedical Services registry data of patients managed by HEMS personnel from April 2015 to March 2020 were analyzed in this retrospective cohort study. HEMS arrival and physicians' interventions at the scene were the variables of interest. The survival rate and neurological outcomes at 28 days after injury were analyzed.
Of the 55 299 registered patients, 722 who experienced prehospital TCA were included in the analysis. The distribution of first-witnessed TCA was as follows: pre-emergency medical service (EMS) arrival (n = 426/722, 60.3%), after EMS arrival (n = 113/722, 16.0%), and after HEMS arrival (n = 168/722, 23.8%). The 28-day survival rate was 6.2% (n = 44/706), with a cerebral performance category of 1 or 2 in 18 patients. However, patients who experienced TCA after receiving interventions provided by physicians before HEMS arrival had the worst outcomes, with only 0.6% of them surviving with favorable neurological outcomes. Multivariable analysis revealed that securing the intravenous route by the EMS team (adjusted odds ratio: 2.43, 95% confidence interval [CI]: 1.11-5.30) and tranexamic acid infusion by the HEMS team (adjusted odds ratio: 2.78, 95% CI: 1.16-6.64) may have increased the return of spontaneous circulation (ROSC) rate.
The results of our study were similar to those reported in previous studies with regards to the use of HEMS in Japan for transporting patients with TCA. Our findings suggest that in patients with severe trauma, cardiac arrest after initiation of HEMS, the highest level of prehospital medical intervention, may be associated with an inferior prognosis. Tracheal intubation and administration of tranexamic acid by the EMS team may increase the rate of ROSC in TCA.
创伤性心脏骤停(TCA)的预后较差。直升机紧急医疗服务(HEMS)常用于将重症患者转运至医院。然而,HEMS在TCA治疗中的作用仍不明确。因此,在本研究中,我们旨在确定日本由HEMS人员管理的院前TCA患者的现状,并比较HEMS到达前后发生TCA的患者的预后。
在这项回顾性队列研究中,分析了日本航空医疗服务协会2015年4月至2020年3月期间由HEMS人员管理的患者登记数据。HEMS到达情况和医生在现场的干预措施是感兴趣的变量。分析了受伤后28天的生存率和神经功能结局。
在55299名登记患者中,722名经历过院前TCA的患者被纳入分析。首次目击者发现TCA的分布情况如下:紧急医疗服务(EMS)到达前(n = 426/722,60.3%)、EMS到达后(n = 113/722,16.0%)以及HEMS到达后(n = 168/722,23.8%)。28天生存率为6.2%(n = 44/706),18名患者的脑功能分类为1级或2级。然而,在HEMS到达前接受医生干预后发生TCA的患者预后最差,只有0.6%的患者存活且神经功能良好。多变量分析显示,EMS团队建立静脉通路(调整后的比值比:2.43,95%置信区间[CI]:1.11 - 5.30)和HEMS团队输注氨甲环酸(调整后的比值比:2.78,95%CI:1.16 - 6.64)可能会提高自主循环恢复(ROSC)率。
我们的研究结果与之前关于日本使用HEMS转运TCA患者的研究报告结果相似。我们的研究结果表明,在严重创伤患者中,在最高级别的院前医疗干预即HEMS启动后发生心脏骤停,可能与较差的预后相关。EMS团队进行气管插管和给予氨甲环酸可能会提高TCA患者的ROSC率。