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2023 韩国内分泌学会原发性醛固酮增多症诊断与管理共识指南。

2023 Korean Endocrine Society Consensus Guidelines for the Diagnosis and Management of Primary Aldosteronism.

机构信息

Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.

出版信息

Endocrinol Metab (Seoul). 2023 Dec;38(6):597-618. doi: 10.3803/EnM.2023.1789. Epub 2023 Oct 13.

Abstract

Primary aldosteronism (PA) is a common, yet underdiagnosed cause of secondary hypertension. It is characterized by an overproduction of aldosterone, leading to hypertension and/or hypokalemia. Despite affecting between 5.9% and 34% of patients with hypertension, PA is frequently missed due to a lack of clinical awareness and systematic screening, which can result in significant cardiovascular complications. To address this, medical societies have developed clinical practice guidelines to improve the management of hypertension and PA. The Korean Endocrine Society, drawing on a wealth of research, has formulated new guidelines for PA. A task force has been established to prepare PA guidelines, which encompass epidemiology, pathophysiology, clinical presentation, diagnosis, treatment, and follow-up care. The Korean clinical guidelines for PA aim to deliver an evidence-based protocol for PA diagnosis, treatment, and patient monitoring. These guidelines are anticipated to ease the burden of this potentially curable condition.

摘要

原发性醛固酮增多症(PA)是继发性高血压的一种常见但未被充分诊断的病因。其特征为醛固酮过度产生,导致高血压和/或低血钾。尽管影响了 5.9%至 34%的高血压患者,但由于缺乏临床意识和系统筛查,PA 经常被漏诊,这可能导致严重的心血管并发症。为了解决这个问题,医学协会制定了临床实践指南,以改善高血压和 PA 的管理。韩国内分泌学会借鉴了大量研究成果,为 PA 制定了新的指南。一个工作组已经成立,负责制定 PA 指南,涵盖流行病学、病理生理学、临床表现、诊断、治疗和随访护理。韩国原发性醛固酮增多症临床指南旨在为 PA 的诊断、治疗和患者监测提供循证方案。这些指南有望减轻这种潜在可治愈疾病的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/631d/10765003/4539bf097840/enm-2023-1789f1.jpg

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