Xu Wen-Bin, Sun Nai-Kun, Cai Di-Xin, Chen Ding-Qiang, Niu Yuan, Jia Fang, Lin Guang-Xun, Rui Gang
Department of Orthopedics, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
The Third Clinical Medical College, Fujian Medical University, Fuzhou, China.
Front Oncol. 2023 Sep 27;13:1259508. doi: 10.3389/fonc.2023.1259508. eCollection 2023.
Spinal meningioma is a common intraspinal tumor, which mainly occurs in the thoracic spine. Ossified meningioma (OSM) is an extremely rare histological variant. Our article reports a rare patient with dorsal complete OSM and reviews this subject.
A 68-year-old woman presented with a one-year history of progressive weakness in both lower limbs with gait disturbance. Physical examination revealed hypoesthesia with a sensory level below T10. Babinski and pathological signs on both sides were weakly positive. Magnetic resonance imaging (MRI) showed a mass at the T10 to T11 level causing severe compression of the spinal cord. Computed tomography (CT) showed complete ossification of the mass. 18F-Fluoro-deoxy-glucose positron emission tomography CT (18F-FDG PET/CT) scan combined with MRI revealed that the mass was an intradural extramedullary high-density ossified nodule. The patient underwent a gross total resection of the mass and pathologic examination indicated that the mass was a meningioma with diffused psammomatous bodies.
We identified a rare case of dorsal complete OSM occurring in a 68-year-old woman. After complete surgical resection, although there were complications such as cerebral fluid leakage and fever, the patient finally recovered with a satisfactory result.
脊髓脑膜瘤是一种常见的脊髓内肿瘤，主要发生于胸椎。骨化性脑膜瘤（OSM）是一种极其罕见的组织学变异类型。我们的文章报道了一例罕见的伴有背部完全骨化性脑膜瘤的患者，并对该病例进行回顾。
一名68岁女性，有一年双下肢进行性无力伴步态障碍病史。体格检查发现T10以下感觉减退。双侧巴氏征及病理征弱阳性。磁共振成像（MRI）显示T10至T11水平有一肿块，导致脊髓严重受压。计算机断层扫描（CT）显示肿块完全骨化。18F-氟脱氧葡萄糖正电子发射断层扫描CT（18F-FDG PET/CT）联合MRI显示肿块为硬膜内髓外高密度骨化结节。患者接受了肿块全切术，病理检查表明肿块是一个伴有弥漫性砂粒体的脑膜瘤。
我们发现了一例罕见的发生于68岁女性的背部完全骨化性脑膜瘤病例。完全手术切除后，尽管出现了脑脊液漏和发热等并发症，但患者最终康复，结果令人满意。
