Hoang Roberts Ly, Zwaans Bernadette M M, Jabbar Kausar, Bartolone Sarah N, Padmanabhan Priya, Peters Kenneth M
Department of Urology, Corewell Health, Royal Oak, MI, USA.
Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
Urol Case Rep. 2023 Sep 25;51:102575. doi: 10.1016/j.eucr.2023.102575. eCollection 2023 Nov.
A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3-4 months after SARS-CoV-2 infection. A bladder biopsy showed urothelial mucosa and submucosa with hemorrhage and fibrin microthrombi in blood vessels. Hydrodistention of the bladder and pelvic floor physical therapy resolved symptoms, though bladder and pain symptoms returned upon reinfection with SARS-CoV-2. Urinalysis revealed elevated urinary interleukin-8, which may indicate localized bladder inflammation.
一名45岁男性，患有糖尿病、高血压和高脂血症，在感染新型冠状病毒2个月后，因持续出现尿频、尿急、夜尿、勃起功能障碍以及膀胱、骨盆和会阴区域持续疼痛等症状，被转诊至泌尿外科。膀胱活检显示膀胱黏膜和黏膜下层有出血，血管内有纤维蛋白微血栓。膀胱水扩张术和盆底物理治疗缓解了症状，但再次感染新型冠状病毒2后，膀胱和疼痛症状又复发了。尿液分析显示尿白细胞介素-8升高，这可能表明膀胱存在局部炎症。
