Bruccoleri Robert E, Oakeley Edward J, Faust Ann Marie E, Altorfer Marc, Dessus-Babus Sophie, Burckhardt David, Oertli Mevion, Naumann Ulrike, Petersen Frank, Wong Joanne
Congenomics, LLC, Glastonbury, CT, USA.
Novartis Institutes for BioMedical Research, Novartis Campus, 4056, Basel, Switzerland.
GigaByte. 2023 Oct 5;2023:gigabyte94. doi: 10.46471/gigabyte.94. eCollection 2023.
Irises are perennial plants, representing a large genus with hundreds of species. While cultivated extensively for their ornamental value, commercial interest in irises lies in the secondary metabolites present in their rhizomes. The Dalmatian Iris ( Lam.) is an ornamental plant that also produces secondary metabolites with potential value to the fragrance and pharmaceutical industries. In addition to providing base notes for the fragrance industry, iris tissues and extracts possess antioxidant, anti-inflammatory and immunomodulatory effects. However, study of these secondary metabolites has been hampered by a lack of genomic information, requiring difficult extraction and analysis techniques. Here, we report the genome sequence of Lam., generated with Pacific Bioscience long-read sequencing, resulting in a 10.04-Gbp assembly with a scaffold N50 of 14.34 Mbp and 91.8% complete BUSCOs. This reference genome will allow researchers to study the biosynthesis of these secondary metabolites in much greater detail, opening new avenues of investigation for drug discovery and fragrance formulations.
鸢尾是多年生植物,是一个包含数百个物种的大属。虽然因其观赏价值而被广泛种植,但鸢尾的商业价值在于其根茎中存在的次生代谢产物。达尔马提亚鸢尾(Iris pallida Lam.)是一种观赏植物,其产生的次生代谢产物对香料和制药行业具有潜在价值。除了为香料行业提供基调外,鸢尾组织和提取物还具有抗氧化、抗炎和免疫调节作用。然而,由于缺乏基因组信息,对这些次生代谢产物的研究受到了阻碍,需要困难的提取和分析技术。在这里,我们报告了达尔马提亚鸢尾(Iris pallida Lam.)的基因组序列,该序列是通过太平洋生物科学公司的长读长测序生成的,得到了一个10.04 Gbp的组装体,支架N50为14.34 Mbp,完整的BUSCOs为91.8%。这个参考基因组将使研究人员能够更详细地研究这些次生代谢产物的生物合成,为药物发现和香料配方开辟新的研究途径。