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[Retracted] miR‑25 promotes metastasis via targeting FBXW7 in esophageal squamous cell carcinoma.[撤回] miR-25通过靶向食管鳞状细胞癌中的FBXW7促进转移。
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[撤回] miR-25通过靶向食管鳞状细胞癌中的FBXW7促进转移。

[Retracted] miR‑25 promotes metastasis via targeting FBXW7 in esophageal squamous cell carcinoma.

作者信息

Hua Ye, Zhao Kai, Tao Gang, Dai Chunhua, Su Yuting

机构信息

Institute of Oncology, Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, Jiangsu 212001, P.R. China.

Department of Gastroenterology, Changzhou Jintan People's Hospital, Changzhou, Jiangsu 213200, P.R. China.

出版信息

Oncol Rep. 2023 Dec;50(6). doi: 10.3892/or.2023.8644. Epub 2023 Oct 13.

DOI:10.3892/or.2023.8644
PMID:37830165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10603550/
Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that a large number of data panels showing cell migration and invasion assay data in Figs. 3C and 5 contained overlapping sections, such that data that were intended to show results obtained under different experimental conditions may have been derived from a smaller number of original sources. In addition, certain of the data in this pair of figures were strikingly similar to data that were submitted for publication in another journal at around the same time as the above paper was submitted to . Finally, regarding the western blotting data shown in Fig. 4B, an obvious splice in the gel strip was noticed for the FBXW7 bands, whereas no equivalent splice was present in the associated GADPH loading control, suggesting that these data originated from different gels. Owing to the fact that the contentious data in the above article were under consideration for publication at around the time that this was submitted to , in addition the other features of concern regarding the data, the Editor has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 38: 3030‑3038, 2017; DOI: 10.3892/or.2017.5995].

摘要

上述论文发表后,一位关注此事的读者提醒编辑注意,图3C和图5中大量显示细胞迁移和侵袭实验数据的数据面板包含重叠部分,以至于旨在展示在不同实验条件下获得的结果的数据可能来自较少数量的原始来源。此外,这组图中的某些数据与在上述论文提交给同一期刊的同时提交给另一家期刊发表的数据惊人地相似。最后,关于图4B所示的蛋白质印迹数据,FBXW7条带在凝胶条上有明显的拼接痕迹,而相关的GADPH上样对照中没有等效的拼接,这表明这些数据来自不同的凝胶。由于上述文章中有争议的数据在提交给本期刊时正在考虑发表,再加上数据方面的其他令人担忧的特征,编辑决定鉴于对所呈现数据缺乏信心,应从本期刊撤回这篇论文。已要求作者对这些问题作出解释,但编辑部未收到回复。编辑就由此造成的不便向读者表示歉意。[《肿瘤学报道》38: 3030 - 3038, 2017; DOI: 10.3892/or.2017.5995]