一种温度敏感、高粘性的医用胶带：一项对比、单盲的临床试验。
A temperature-sensitive, high-adhesion medical tape: a comparative, single-blind clinical trial.
机构信息
Human Photonics Laboratory, Department of Mechanical Engineering, University of Washington, Seattle, WA, US.
Washington Clean Energy Testbeds, University of Washington, Seattle, WA, US.
出版信息
J Wound Care. 2023 Oct 2;32(10):665-675. doi: 10.12968/jowc.2023.32.10.665.
OBJECTIVE
Medical adhesives are used to secure wound care dressings and other critical devices to the skin. While high peel-strength adhesives provide more secure skin attachment, they are difficult to remove from the skin and are correlated with medical adhesive-related skin injuries (MARSI), including skin tears, and an increased risk of infection. Lower-adhesion medical tapes may be applied to avoid MARSI, leading to dressing or device dislodgement and further medical complications.
METHOD
This paper reports on the clinical testing of a new, high-adhesion medical tape, ThermoTape (University of Washington, US), designed for low skin trauma upon release. ThermoTape was benchmarked with Tegaderm (3M, US) and Kind Removal Tape (KRT) (3M, US). All three tapes were applied to both the left and right forearm of healthy volunteers and were removed 24 hours later-the right arm without applying heat and the left arm by applying a heat pack for 30 seconds before removal. Tape wear, self-reported pain (0-10 scale) and skin redness 15 minutes after removal were recorded.
RESULTS
This was a 53-subject comparative, single-blind clinical trial. There were clinically and statistically significant results supporting reduced pain during removal of ThermoTape with warming, with an average 58% decrease in pain, paired with a statistically significant 45% reduction in skin redness (p<0.01 for both values). In contrast, there were statistically insignificant differences in pain and redness for removal of Tegaderm and KRT with warming. ThermoTape after warming, in comparison with Tegaderm without warming, produced a reduced pain score of >1 on the 0-10 Wong-Baker/Face pain scale, which was statistically significant (p<0.01).
CONCLUSION
These results provide compelling evidence that warming ThermoTape prior to removal can reduce pain and injury when compared with standard medical tapes. This could allow for stronger attachment of wound care dressings and critical medical devices while reducing cases of MARSI.
目的
医用黏合剂用于将伤口护理敷料和其他关键器械固定在皮肤上。虽然高剥离强度的黏合剂可以提供更牢固的皮肤附着，但它们很难从皮肤上移除，并与医用黏合剂相关的皮肤损伤（MARSI）相关，包括皮肤撕裂和感染风险增加。低附着力的医用胶带可用于避免 MARSI，导致敷料或器械脱落，并进一步引发医疗并发症。
方法
本文报告了一种新的高附着力医用胶带 ThermoTape（美国华盛顿大学）的临床测试结果，该胶带旨在降低释放时的皮肤创伤。ThermoTape 与 Tegaderm（3M，美国）和 Kind Removal Tape（KRT）（3M，美国）进行了对比。将所有三种胶带均应用于健康志愿者的左右前臂，24 小时后去除胶带，右臂不加热，左臂在去除前用热包加热 30 秒。记录胶带的磨损、自我报告的疼痛（0-10 分制）以及去除后 15 分钟的皮肤发红情况。
结果
这是一项 53 名受试者的对比性、单盲临床试验。有临床和统计学意义的结果支持在使用热包加热 ThermoTape 去除时减轻疼痛，疼痛减轻平均 58%，皮肤发红程度降低 45%（两者均为 p<0.01）。相比之下，Tegaderm 和 KRT 在加热去除时，疼痛和发红程度没有统计学差异。与未加热的 Tegaderm 相比，加热后的 ThermoTape 在 0-10 Wong-Baker/Face 疼痛量表上产生了>1 的疼痛评分降低，具有统计学意义（p<0.01）。
结论
这些结果提供了有力的证据，表明与标准医用胶带相比，在去除前加热 ThermoTape 可以减轻疼痛和损伤。这可以使伤口护理敷料和关键医疗设备更牢固地固定，同时减少 MARSI 病例。
Zotero 插件