Tohoku Medical Megabank Organization, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Graduate School of Medicine, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan.
Hypertens Res. 2023 Dec;46(12):2718-2728. doi: 10.1038/s41440-023-01454-0. Epub 2023 Oct 13.
This study aimed to examine whether risk of withdrawal from HTTx was higher in coastal areas that were severely damaged by tsunami than in inland areas. We conducted a cross-sectional study of 9218 participants aged ≥20 years in Miyagi, Japan. The odds ratios (ORs) and confidence interval (CI) for withdrawal from HTTx in coastal and inland groups were compared using multivariate logistic regression analysis, adjusting for potential confounders. In total, 194 of 5860 and 146 of 3358 participants in the inland and coastal groups, respectively, withdrew from HTTx treatment. OR (95%CI) of withdrawal from HTTx in the coastal group was 1.46 (1.14-1.86) compared to the inland group. According to housing damage, ORs (95% CI) in the no damage, partially destroyed, and more than half destroyed coastal groups compared with the no damage inland group were 1.62 (1.04-2.50), 1.69 (1.17-2.45), and 1.08 (0.71-1.65), respectively. In conclusion, the risk of HTTx withdrawal for participants whose homes in coastal areas were relatively less damaged was significantly higher compared with those in inland areas, while the risk of HTTx withdrawal for participants whose homes were more than half destroyed was not. Post-disaster administrative support for disaster victims is considered vital for continuation of their treatment.
本研究旨在探讨海啸受灾严重的沿海地区与内陆地区相比，HTTx 停药风险是否更高。我们对日本宫城县≥20 岁的 9218 名参与者进行了一项横断面研究。使用多变量逻辑回归分析比较沿海组和内陆组 HTTx 停药的比值比（OR）和置信区间（CI），并调整了潜在混杂因素。在内陆组和沿海组中，分别有 194/5860 和 146/3358 名参与者停止了 HTTx 治疗。与内陆组相比，沿海组停止 HTTx 治疗的 OR（95%CI）为 1.46（1.14-1.86）。根据住房受损情况，与内陆组无受损住房相比，无受损、部分受损和受损过半的沿海组的 ORs（95%CI）分别为 1.62（1.04-2.50）、1.69（1.17-2.45）和 1.08（0.71-1.65）。总之，与内陆地区相比，沿海地区住房受损相对较轻的参与者停止 HTTx 治疗的风险明显更高，而住房受损过半的参与者停止 HTTx 治疗的风险则没有明显增加。为受灾灾民提供灾后行政支持被认为对他们继续接受治疗至关重要。
