Kodama Eiichi N, Taira Makiko, Kiyomoto Hideyasu, Nakamura Tomohiro, Nagaie Satoshi, Kuriyama Shinichi, Hozawa Atsushi, Sugawara Junichi, Nagami Fuji, Uruno Akira, Nakaya Jun, Metoki Hirohito, Sakaida Masaki, Kikuya Masahiro, Suzuki Yoichi, Ito Kiyoshi, Hamanaka Yohei, Suzuki Kichiya, Kure Shigeo, Yaegashi Nobuo, Fuse Nobuo, Shimizu Ritsuko, Yamamoto Masayuki
Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Graduate School of Medicine, Tohoku University, Sendai, Japan.
JMA J. 2024 Jul 16;7(3):342-352. doi: 10.31662/jmaj.2023-0215. Epub 2024 Jul 8.
The Tohoku Medical Megabank (TMM) was established for creative reconstruction from the Great East Japan Earthquake and tsunami in 2011. Two prospective genome cohort studies in Miyagi prefecture have successfully recruited approximately 127,000 participants. The health status of these individuals was evaluated at the initial recruitment, and follow-up health checkups have been conducted every 5 years. During these health checkups, unexpected critical values were encountered, which prompted us to develop an urgent notification system.
We analyzed the frequency of critical values observed in home blood pressure (HBP) test in an urgent notification office (UNO). We returned the critical values by urgent notification before the notifications of regular results. In addition, the impact of the TMM urgent notification on the participants was evaluated.
We issued urgent notifications of the critical values of extremely high HBP. Of the 21,061 participants who underwent HBP measurements, 256 (1.2%) met the criteria for urgent notification. It was found that abnormalities in blood sugar levels, renal function, and lipid values were frequently concurrent with the abnormal HBP readings. Annual questionnaires administered after the urgent notification, approximately 60% of those went to hospitals or clinics.
The urgent notification system for hypertensive emergency with HBP in the TMM was well accepted by the participants and encouraged them to seek medical care. The system has been useful in addressing the prolonged healthcare problems and in promoting health care in large-scale disaster damaged areas.
东北医学综合数据库（TMM）于2011年为从东日本大地震和海啸中进行创新性重建而设立。宫城县的两项前瞻性基因组队列研究已成功招募了约12.7万名参与者。这些个体的健康状况在初次招募时进行了评估，并每5年进行一次后续健康检查。在这些健康检查期间，遇到了意外的危急值，这促使我们开发了一个紧急通知系统。
我们分析了在紧急通知办公室（UNO）进行的家庭血压（HBP）测试中观察到的危急值频率。我们在常规结果通知之前通过紧急通知返回危急值。此外，评估了TMM紧急通知对参与者的影响。
我们发布了极高HBP危急值的紧急通知。在21061名进行HBP测量的参与者中，256人（1.2%）符合紧急通知标准。发现血糖水平、肾功能和血脂值异常经常与异常的HBP读数同时出现。紧急通知后每年进行问卷调查，约60%的人前往医院或诊所就诊。
TMM中针对高血压急症的HBP紧急通知系统得到了参与者的认可，并鼓励他们寻求医疗护理。该系统有助于解决长期的医疗保健问题，并促进大规模受灾地区的医疗保健。
