Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Iran.
The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
BMC Public Health. 2023 Oct 13;23(1):2001. doi: 10.1186/s12889-023-16950-8.
A significant proportion of the global burden of disability and premature mortality has caused by hypertension. It seems that the relationship between obesity and hypertension is not only associated with excessive body fat mass (FM) but also with body adipose distribution patterns. The present study investigated the association between regional fat distribution using dual-energy X-ray absorptiometry and hypertension in older adults.
This cross-sectional study was performed using the data from Bushehr Elderly Health Program (BEH) on a total of 2419 participants aged 60 and over. Hypertension was defined as SBP of at least 140 mmHg and/or DBP of at least 90 mmHg. SBP between 120 and 139 mmHg and/or a DBP between 80 and 89 mmHg were considered prehypertension. Participants underwent body composition measurement by dual-energy x-ray absorptiometry to analyze FM, fat-free mass (FFM) in trunk and extremities composition.
The results showed that 460 (19.02%) of participants had prehypertension, and 1,818 (75.15% ) had hypertension. The odds of having prehypertension (OR: 1.06, 95%CI: 1.01-1.12) and hypertension (OR: 1.08, 95%CI: 1.03-1.13) increased with a rise in total body FM percentage. Moreover, people with a higher FM to FFM ratio had increased odds of being prehypertensive (OR: 9.93, 95%CI: 1.28-76.99) and hypertensive (OR: 16.15, 95%CI: 2.47-105.52). Having a higher android to gynoid FM ratio was related to increased odds of being prehypertensive and hypertensive.
This study showed that a higher body FM, particularly in the android region, is associated with higher odds of having hypertension in older adults.
全球范围内，大量的残疾和过早死亡负担是由高血压引起的。似乎肥胖与高血压之间的关系不仅与过多的体脂肪量（FM）有关，还与身体脂肪分布模式有关。本研究使用双能 X 射线吸收法（DXA）评估局部脂肪分布与老年人高血压之间的关系。
本横断面研究使用来自 Bushehr 老年人健康计划（BEH）的数据，共纳入 2419 名年龄在 60 岁及以上的参与者。高血压定义为收缩压（SBP）至少 140mmHg 和/或舒张压（DBP）至少 90mmHg。SBP 在 120-139mmHg 和/或 DBP 在 80-89mmHg 之间被认为是前期高血压。参与者接受了双能 X 射线吸收法的身体成分测量，以分析 FM、躯干和四肢的去脂体重（FFM）组成。
结果显示，460 名（19.02%）参与者患有前期高血压，1818 名（75.15%）患有高血压。随着全身 FM 百分比的增加，患有前期高血压（OR：1.06，95%CI：1.01-1.12）和高血压（OR：1.08，95%CI：1.03-1.13）的几率也随之增加。此外，FM 与 FFM 比值较高的人群患前期高血压（OR：9.93，95%CI：1.28-76.99）和高血压（OR：16.15，95%CI：2.47-105.52）的几率也增加。较高的男性型向女性型 FM 比值与较高的前期高血压和高血压患病几率有关。
本研究表明，老年人全身 FM 较高，特别是男性型区域的 FM 较高，与高血压的患病几率较高有关。
