Department of Exercise Sciences, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Int J Environ Res Public Health. 2023 Oct 2;20(19):6872. doi: 10.3390/ijerph20196872.
Telomere length is a good index of cellular aging. Longer telomeres are predictive of longer life, and healthy lifestyles are associated with longer telomeres. This study explored the relationship between time spent jogging or running each week and leukocyte telomere length (LTL) in 4458 randomly selected U.S. adults. The association was studied using data collected by the National Health and Nutrition Examination Survey (NHANES), and a cross-sectional design. Total weekly jog/run time was calculated from survey responses. From the minute totals, three categories were formed: <10 min/week, 10-74 min/week, and ≥75 min/week. Adults in the third category met the U.S. guidelines. Data were analyzed using one-way ANOVA. Partial correlation was used to adjust for differences in potential mediating factors, including demographic and lifestyle/medical factors. In the total sample, after adjusting for all the potential covariates, mean LTL significantly differed across the three jog/run categories (F = 4.1, = 0.0272). Specifically, adults who met the guidelines via jogging and/or running had significantly longer telomeres than adults who performed no jogging/running. Adults in the middle category did not differ from the other two categories. A minimum of 75 min of jogging/running weekly is predictive of longer telomeres when compared to adults who do not jog or run regularly.
端粒长度是细胞衰老的一个很好的指标。较长的端粒预示着寿命更长,健康的生活方式与较长的端粒有关。本研究探讨了每周慢跑或跑步时间与 4458 名随机选择的美国成年人白细胞端粒长度(LTL)之间的关系。该关联使用国家健康和营养检查调查(NHANES)收集的数据和横断面设计进行了研究。每周总慢跑/跑步时间是根据调查回答计算得出的。从分钟总数中,形成了三个类别:<10 分钟/周、10-74 分钟/周和≥75 分钟/周。第三类成年人符合美国指南。使用单向方差分析对数据进行了分析。偏相关用于调整潜在中介因素的差异,包括人口统计学和生活方式/医疗因素。在总样本中,在调整了所有潜在协变量后,三个慢跑/跑步类别之间的平均 LTL 差异显著(F = 4.1,p = 0.0272)。具体来说,通过慢跑和/或跑步达到指南要求的成年人的端粒明显比不进行慢跑/跑步的成年人的端粒长。中间组的成年人与其他两组没有区别。与不经常慢跑或跑步的成年人相比,每周至少进行 75 分钟的慢跑/跑步可预测端粒更长。