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通过空间和时间分辨分析揭示卵巢癌代谢的见解

Unveiling Insights into Ovarian Cancer Metabolism through Space- and Time-Resolved Analysis.

作者信息

Jia Wei, Li Mengci

机构信息

School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong 999077, Hong Kong.

Center for Translational Medicine and Shanghai Key Laboratory of Diabetes Mellitus, The Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.

出版信息

Cancers (Basel). 2023 Oct 8;15(19):4881. doi: 10.3390/cancers15194881.

DOI:10.3390/cancers15194881
PMID:37835575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10572059/
Abstract

High-grade serous carcinoma (HGSC) represents a formidable challenge in the realm of ovarian cancer, notorious for its elusive early detection, poor prognosis and limited understanding of the intricacies of its pathogenesis [...].

摘要

高级别浆液性癌（HGSC）是卵巢癌领域的一项严峻挑战，因其早期检测困难、预后不良以及对其发病机制复杂性的了解有限而声名狼藉[……]

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本文引用的文献

1
Immunobiology of high-grade serous ovarian cancer: lessons for clinical translation.高级别浆液性卵巢癌的免疫生物学：临床转化的启示。
Nat Rev Cancer. 2022 Nov;22(11):640-656. doi: 10.1038/s41568-022-00503-z. Epub 2022 Sep 15.
2
Space- and Time-Resolved Metabolomics of a High-Grade Serous Ovarian Cancer Mouse Model.高级别浆液性卵巢癌小鼠模型的空间和时间分辨代谢组学
Cancers (Basel). 2022 Apr 30;14(9):2262. doi: 10.3390/cancers14092262.
3
A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer.一种新型双脂质特征是卵巢癌的强大独立预后因素。
Cancers (Basel). 2021 Apr 7;13(8):1764. doi: 10.3390/cancers13081764.
4
Deep Metabolomics of a High-Grade Serous Ovarian Cancer Triple-Knockout Mouse Model.高级别浆液性卵巢癌三敲除小鼠模型的深度代谢组学研究。
J Proteome Res. 2019 Aug 2;18(8):3184-3194. doi: 10.1021/acs.jproteome.9b00263. Epub 2019 Jul 10.
5
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer.人类高级别浆液性卵巢癌的综合蛋白质基因组特征分析
Cell. 2016 Jul 28;166(3):755-765. doi: 10.1016/j.cell.2016.05.069. Epub 2016 Jun 29.
6
The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice.在小鼠中，卵巢是高级别浆液性卵巢癌的另一个起源部位。
Endocrinology. 2015 Jun;156(6):1975-81. doi: 10.1210/en.2014-1977. Epub 2015 Mar 27.
7
Integrated genomic analyses of ovarian carcinoma.卵巢癌的综合基因组分析。
Nature. 2011 Jun 29;474(7353):609-15. doi: 10.1038/nature10166.