Centro de Investigación en Biomoléculas-CIBIMOL, Laboratorio de Cromatografía y Espectrometría de Masas-CROM-MASS, Universidad Industrial de Santander, Bucaramanga 680002, Colombia.
Real Jardín Botánico-CSIC, Claudio Moyano 1, 28014 Madrid, Spain.
Molecules. 2023 Sep 22;28(19):6767. doi: 10.3390/molecules28196767.
(Lamiaceae family), a species also treated as in a recently segregated genus from , is a perennial herb or subshrub native to the Andes of northern South America. leaves are commonly used in traditional medicine to treat respiratory and digestive illnesses. In this study, plants at different phenological stages (vegetative, flowering, and post-flowering) were harvested to obtain essential oils (EOs) and extracts (from fresh plant materials or post-distillation waste) whose chemical compositions and antioxidant activities were determined. EOs distilled by microwave-assisted hydrodistillation were analyzed by GC/MS/FID, and hydroalcoholic extracts obtained from fresh plant materials or post-distillation waste were analyzed by UHPLC-ESI-Orbitrap-MS. The antioxidant activity was evaluated by the ABTS and ORAC assays. The principal compounds found in EOs were sesquiterpene hydrocarbons (65%); specifically, ()-β-caryophyllene and germacrene D. Pyranone, rosmarinic acid, rutin, and -hydroxybenzoic acid were the main constituents in extracts. After analyzing the chemical composition and antioxidant activity (ORAC) of EOs and hydroethanolic extracts from flowering plants, minimal variations were found. It is advisable to harvest plants during their flowering stage to acquire EOs and extracts that can be utilized in the agro-industry of EOs and their natural derivatives.
唇形科（Lamiaceae family），一种也被处理为 的最近分离属的物种，是一种原产于南美洲北部安第斯山脉的多年生草本植物或亚灌木。 植物的叶子通常用于传统医学治疗呼吸道和消化系统疾病。在这项研究中，收获了不同物候阶段（营养生长、开花和开花后）的 植物，以获得精油（EOs）和提取物（来自新鲜植物材料或蒸馏后的废物），并测定其化学成分和抗氧化活性。用微波辅助水蒸馏法蒸馏的精油通过 GC/MS/FID 进行分析，从新鲜植物材料或蒸馏后的废物中获得的水醇提取物通过 UHPLC-ESI-Orbitrap-MS 进行分析。抗氧化活性通过 ABTS 和 ORAC 测定法进行评估。精油中的主要化合物为半萜类化合物（65％）；具体来说，（）-β-石竹烯和大根香叶烯 D。吡喃酮、迷迭香酸、芦丁和 -羟基苯甲酸是 提取物的主要成分。分析开花 植物的精油和水醇提取物的化学成分和抗氧化活性（ORAC）后，发现变化很小。建议在植物开花期收获 植物，以获得可用于精油及其天然衍生物的农业产业的精油和提取物。
