Loughlani Rayane-Ichrak, Gamero-Quijano Alonso, Montilla Francisco
Departamento de Química Física and Instituto Universitario de Materiales de Alicante (IUMA), Universidad de Alicante, Carretera San Vicente s/n, 03690 Alicante, Spain.
Molecules. 2023 Sep 28;28(19):6845. doi: 10.3390/molecules28196845.
The sol-gel method is a straightforward technique that allows electrode modification with silica thin films. Furthermore, the silica pores could be functionalized to enhance the electrical conductivity and reactivity of the silica films. In this context, silica thin films were functionalized with ferrocene species. This functionalization was performed by electroassisted accumulation, generating a micro-structured composite electrode (Fc@SiO electrode). These modified electrodes were characterized by electrochemical and spectroelectrochemical methods, pointing out that ferrocene species were confined with high stability within the microporous silica thin film, demonstrating the good adsorption capacity of the silica. While the spectroelectrochemical characterization indicates that only a fraction of the confined species within the silica films were electroactive, the electrochemical results demonstrate that the Fc@SiO film enhances the electrochemical response of cytochrome c in a solution, which gives rise to further applications of these films for redox-controlled release and electrochemical detection of other redox-active proteins.
溶胶-凝胶法是一种直接的技术，可用于用二氧化硅薄膜对电极进行修饰。此外，二氧化硅孔隙可以进行功能化处理，以提高二氧化硅薄膜的电导率和反应活性。在此背景下，用二茂铁类物质对二氧化硅薄膜进行了功能化处理。这种功能化是通过电辅助积累实现的，从而生成了一种微结构复合电极（Fc@SiO电极）。这些修饰电极通过电化学和光谱电化学方法进行了表征，结果表明二茂铁类物质以高稳定性被限制在微孔二氧化硅薄膜内，这证明了二氧化硅具有良好的吸附能力。虽然光谱电化学表征表明二氧化硅薄膜内只有一部分被限制的物质具有电活性，但电化学结果表明，Fc@SiO薄膜增强了溶液中细胞色素c的电化学响应，这使得这些薄膜在氧化还原控制释放和其他氧化还原活性蛋白的电化学检测方面有了进一步的应用。
