Williams E H, Hayes R J, Smith P G
J Trop Med Hyg. 1986 Aug;89(4):193-211.
An analysis is presented of data on all 30 129 inpatient admissions to a mission hospital in the West Nile District of Uganda in the 27 year period from July 1951 to August 1978. For most of this period the hospital was staffed by the same two doctors. For each patient admitted, a record was made of their age (adult or child), sex, place of residence, duration of stay in hospital, diagnosis and vital status at discharge. The annual number of admissions increased steadily from around 300 in 1952 to over 1600 in 1966 and subsequently declined to about 900 in 1977. Sixty-five per cent of admissions were medical, 12% surgical, 11% obstetric and 9% gynaecological. Thirty per cent of admissions were children (aged 0-9 years). Forty-five per cent of admissions were from those resident in the same county as the hospital and another 20% were from an immediately adjacent county. Infective and parasitic conditions (including respiratory diseases) accounted for over 60% of admissions among children and over 38% of admissions among adults (excluding obstetric patients). The six most common causes of admission were: uncomplicated delivery (2308 admissions), pneumonia (2020), hookworm (1999), malaria (1806), schistosomiasis (1742) and diarrhoea (1041). In total 1960 deaths were recorded (6.5% of all admissions). High case fatality rates were observed for tetanus (61%), immaturity (54%), meningitis (38%), kwashiorkor (21%), other malnutrition (19%) and anaemia (19%). A striking increase in the number of admissions for measles was observed in the period 1976 to 1978. Admission rates for schistosomiasis (S. mansoni) appeared to be highest from counties adjacent to the Nile and 104 deaths were recorded among the 1742 patients with this as the primary diagnosis. Admissions for diabetes, as a percentage of all admissions increased from 0.2% in 1951-54 to 1.5% at the end of the study period. Marked seasonal variations in admission patterns were found for diarrhoea, measles, meningitis and respiratory infections, the last two, but not diarrhoea, being most common in the wettest months. Admissions for malaria showed no strong seasonal associations. Despite the limitations of hospital-based data, it is argued that the data analysed provide a reasonable indication of the important causes of severe morbidity and mortality in the district. Furthermore, some of the changes in admission patterns over time are likely to represent true changes in disease rates rather than artefacts of diagnosis or referral. The analyses presented indicate the value of simple record systems, carefully maintained.
对1951年7月至1978年8月这27年间乌干达西尼罗河地区一家教会医院的30129例住院病例数据进行了分析。在此期间的大部分时间里,医院由同两名医生坐诊。对于每一位入院患者,都记录了他们的年龄(成人或儿童)、性别、居住地、住院时间、诊断结果以及出院时的生命体征。入院人数从1952年的约300人稳步增加到1966年的1600多人,随后在1977年降至约900人。65%的入院病例为内科疾病,12%为外科疾病,11%为产科疾病,9%为妇科疾病。30%的入院患者为儿童(0至9岁)。45%的入院患者来自与医院所在县相同的居民,另有20%来自紧邻的县。感染性和寄生虫病(包括呼吸道疾病)占儿童入院病例的60%以上,占成人(不包括产科患者)入院病例的38%以上。最常见的六种入院原因是:顺产(2308例入院)、肺炎(2020例)、钩虫病(1999例)、疟疾(1806例)、血吸虫病(1742例)和腹泻(1041例)。共记录了1960例死亡病例(占所有入院病例的6.5%)。破伤风(61%)、未成熟(54%)、脑膜炎(38%)、夸休可尔症(21%)、其他营养不良(19%)和贫血(19%)的病死率较高。1976年至1978年期间,麻疹入院人数显著增加。血吸虫病(曼氏血吸虫)的入院率似乎在尼罗河附近的县最高,在1742例以该病为主要诊断的患者中记录了104例死亡。糖尿病入院病例占所有入院病例的百分比从1951 - 1954年的0.2%增加到研究期末的1.5%。腹泻、麻疹、脑膜炎和呼吸道感染的入院模式存在明显的季节性变化,后两者(但腹泻不是)在最潮湿的月份最为常见。疟疾入院病例没有明显的季节性关联。尽管基于医院的数据存在局限性,但有人认为所分析的数据合理地表明了该地区严重发病和死亡的重要原因。此外,随着时间推移入院模式的一些变化可能代表疾病发生率的真实变化,而不是诊断或转诊的人为因素。所呈现的分析表明了精心维护的简单记录系统的价值。