Kodaira S, Teramoto T
Gan No Rinsho. 1986 Aug;32(10):1328-32.
Extended radical operation for rectal cancer included the high ligation of inferior mesenteric artery and the dissection of lateral lymph nodes. There was no significant difference between overall survival of extended operation and conventional operation, although in Dukes B cases, 5-year survival rate was significantly higher in extended operation than in conventional. Extended operation caused high incidence of postoperative urinary and sexual dysfunction compared with conventional operation. We conclude that extended radical operation must be performed only in those patients, when tumors locate in the lower part of the rectum and invade beyond the proper muscle layer.
直肠癌扩大根治术包括肠系膜下动脉高位结扎及侧方淋巴结清扫。扩大根治术与传统手术的总生存率无显著差异，尽管在Dukes B期病例中，扩大根治术的5年生存率显著高于传统手术。与传统手术相比，扩大根治术导致术后泌尿及性功能障碍的发生率较高。我们得出结论，仅当肿瘤位于直肠下段且侵犯超过固有肌层时，才应对这些患者实施扩大根治术。
