Watanabe M, Hotchi M
Gan No Rinsho. 1986 Oct;32(12):1610-8.
The patient was a 67-year-old woman, she had lost her public and axillary hair upon menopause at the age of 47, and symptoms of hypothyroidism appeared with cervical tumor one year prior to her death. A diagnosis of anaplastic carcinoma was made by biopsy of the thyroid gland. Laboratory examination revealed a high titer of antithyroid antibody and dysfunction of the thyroid gland, adrenal cortices and pituitary gland. At autopsy, the pituitary gland showed a cup-shaped deformity with atrophy, and the adrenal glands were markedly atrophic. It was considered that the atrophy of the adrenal glands was secondary to dysfunction of the pituitary gland.