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烧伤后脓毒症存活研究

Surviving Sepsis After Burn Campaign.

机构信息

Department of Burns, Shriners Children's Northern California and Department of Surgery, University of California, Davis, Sacramento, CA, USA.

Department of Clinical Pharmacy & Translational Scre have been several studies that have evaluatedience, College of Pharmacy, University of Tennessee, Health Science Center; Memphis, TN, USA.

出版信息

Burns. 2023 Nov;49(7):1487-1524. doi: 10.1016/j.burns.2023.05.003. Epub 2023 May 6.

Abstract

INTRODUCTION

The Surviving Sepsis Campaign was developed to improve outcomes for all patients with sepsis. Despite sepsis being the primary cause of death after thermal injury, burns have always been excluded from the Surviving Sepsis efforts. To improve sepsis outcomes in burn patients, an international group of burn experts developed the Surviving Sepsis After Burn Campaign (SSABC) as a testable guideline to improve burn sepsis outcomes.

METHODS

The International Society for Burn Injuries (ISBI) reached out to regional or national burn organizations to recommend members to participate in the program. Two members of the ISBI developed specific "patient/population, intervention, comparison and outcome" (PICO) questions that paralleled the 2021 Surviving Sepsis Campaign [1]. SSABC participants were asked to search the current literature and rate its quality for each topic. At the Congress of the ISBI, in Guadalajara, Mexico, August 28, 2022, a majority of the participants met to create "statements" based on the literature. The "summary statements" were then sent to all members for comment with the hope of developing an 80% consensus. After four reviews, a consensus statement for each topic was created or "no consensus" was reported.

RESULTS

The committee developed sixty statements within fourteen topics that provide guidance for the early treatment of sepsis in burn patients. These statements should be used to improve the care of sepsis in burn patients. The statements should not be considered as "static" comments but should rather be used as guidelines for future testing of the best treatments for sepsis in burn patients. They should be updated on a regular basis.

CONCLUSION

Members of the burn community from the around the world have developed the Surviving Sepsis After Burn Campaign guidelines with the goal of improving the outcome of sepsis in burn patients.

摘要

简介

为了改善所有脓毒症患者的预后,发起了拯救脓毒症运动。尽管脓毒症是烧伤后首要的死亡原因,但烧伤一直被排除在拯救脓毒症运动之外。为了改善烧伤患者的脓毒症预后,一个国际烧伤专家小组制定了烧伤后脓毒症存活运动(SSABC),作为一个可测试的指南,以改善烧伤脓毒症的结局。

方法

国际烧伤协会(ISBI)联系了区域或国家烧伤组织,建议成员参与该计划。ISBI 的两名成员制定了具体的“患者/人群、干预、比较和结局”(PICO)问题,与 2021 年拯救脓毒症运动相平行[1]。SSABC 参与者被要求搜索当前文献,并对每个主题的质量进行评分。在 2022 年 8 月 28 日于墨西哥瓜达拉哈拉举行的 ISBI 大会上,大多数与会者开会根据文献制定“声明”。然后将这些“总结声明”发送给所有成员征求意见,希望达成 80%的共识。经过四轮审查,针对每个主题制定了一个共识声明或报告“无共识”。

结果

委员会制定了 60 项声明,涉及 14 个主题,为烧伤患者脓毒症的早期治疗提供了指导。这些声明应该用于改善烧伤患者脓毒症的护理。这些声明不应被视为“静态”评论,而应被视为未来测试烧伤患者脓毒症最佳治疗方法的指南。它们应该定期更新。

结论

来自世界各地的烧伤界成员制定了烧伤后脓毒症存活运动指南,目标是改善烧伤患者脓毒症的预后。

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