OneBlood, Scientific, Medical, Technical Direction, Orlando, Florida, USA.
Department of Pathology and Laboratory Medicine; Blood Bank and Therapeutic Apheresis Unit, Roswell Park Comprehensive Cancer Center, and Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA.
Transfusion. 2023 Dec;63(12):2205-2213. doi: 10.1111/trf.17572. Epub 2023 Oct 15.
The demand for blood products sometimes exceeds the available inventory. Blood product inventories are dependent upon the availability of donors, supplies and reagents, and collection staff. During prolonged extreme shortages, blood centers and transfusion services must alter practices to meet the needs of patients.
The Association for the Advancement of Blood and Biotherapies Donor and Blood Component Management Subsection compiled some strategies from its blood center and hospital transfusion service members that could be implemented during blood product shortages.
Some strategies that blood centers could use to increase their available inventories include increasing donor recruitment efforts, using alternate types of collection kits, manufacturing low-yield apheresis-derived platelets and/or whole blood-derived platelets, using cold-stored platelets, transferring inventory internally among centers of the same enterprise, using frozen inventory, decreasing standing order quantities, prioritizing allocation to certain patient populations, filling partial orders, and educating customers and blood center staff. Transfusion service strategies that could be implemented to maximize the use of the limited available inventory include increasing patient blood management efforts, using split units, finding alternate blood suppliers, trading blood products with other hospital transfusion services, developing a patient priority list, assembling a hospital committee to decide on triaging priorities, using expired products in extreme situations, and accepting nonconforming products after performing safety checks.
Blood centers and transfusion services must choose the appropriate strategies to implement based on their needs.
有时对血液制品的需求超过了现有库存。血液制品库存取决于供体、供应品和试剂的可用性以及采集人员。在长时间的极端短缺期间,血液中心和输血服务必须改变做法以满足患者的需求。
血液和生物疗法促进协会(Association for the Advancement of Blood and Biotherapies)的供体和血液成分管理分组从其血液中心和医院输血服务成员那里汇编了一些策略,这些策略可在血液产品短缺期间实施。
血液中心可以用来增加其可用库存的一些策略包括增加献血者招募工作、使用替代类型的采集套件、制造低产的单采衍生血小板和/或全血衍生血小板、使用冷藏血小板、在同一企业的中心之间内部转移库存、使用冷冻库存、减少常备订单数量、优先分配给某些患者群体、部分订单填充,以及教育客户和血液中心工作人员。为了最大限度地利用有限的可用库存,输血服务可以实施的策略包括增加患者血液管理工作、使用拆分单位、寻找替代血液供应商、与其他医院输血服务进行血液产品交易、制定患者优先清单、组建医院委员会决定分诊优先级、在极端情况下使用过期产品以及在进行安全检查后接受不合格产品。
血液中心和输血服务必须根据自身需求选择要实施的适当策略。