卡琪花蒂玛（Benth. & Hook. f.）叶不同溶剂提取物中没食子酸定量及其抗氧化和抗炎活性的数据集。

Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah ( Benth. & Hook. f.) leaves.

作者信息

Awang Mohd Azrie, Benjamin Mohammad Amil Zulhilmi, Anuar Adilah, Ismail Mohd Fakhrulddin, Ramaiya Shiamala Devi, Mohd Hashim Siti Nur Aisyah

机构信息

Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia.

Innovative Food Processing and Ingredient Research Group, Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia.

出版信息

Data Brief. 2023 Oct 5;51:109644. doi: 10.1016/j.dib.2023.109644. eCollection 2023 Dec.

DOI:10.1016/j.dib.2023.109644

PMID:37840993

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10570934/

Abstract

The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah ( Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. Total phenolic content (TPC) was assessed using the Folin-Ciocalteu method. The antioxidant activities were evaluated using xanthine oxidase superoxide (XOD-Superoxide) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays, while anti-inflammatory activities were examined through lipoxygenase (LOX) and xanthine oxidase (XOD) inhibition assays. Results showed that the water-extracted sample had the highest GA and TPC among the solvents tested, along with the strongest inhibition activities in the XOD-Superoxide and DPPH assays. Both water and ethanol extracts showed significant inhibitory activities in the LOX assay but were inactive in the XOD assay. These findings suggest that the bioactivity of leaf extract is associated with GA and TPC. GA and TPC strongly correlated with antioxidant and anti-inflammatory activities, except for the XOD assay. The dataset highlights the potential dietary benefits of leaves as a natural source of antioxidants and anti-inflammatory properties for pharmaceutical and nutraceutical applications.

摘要

本文介绍了使用多种溶剂对卡琪花蒂玛（Benth. & Hook. f.）叶片中的没食子酸（GA）进行定量分析以及评估其抗氧化和抗炎特性的数据。采用高效液相色谱分析法对GA进行定量。使用福林 - 酚法评估总酚含量（TPC）。通过黄嘌呤氧化酶超氧化物（XOD - 超氧化物）和2,2 - 二苯基 - 1 - 苦基肼（DPPH）测定法评估抗氧化活性，同时通过脂氧合酶（LOX）和黄嘌呤氧化酶（XOD）抑制测定法检测抗炎活性。结果表明，在所测试的溶剂中，水提取物的GA和TPC含量最高，并且在XOD - 超氧化物和DPPH测定法中具有最强的抑制活性。水提取物和乙醇提取物在LOX测定法中均显示出显著的抑制活性，但在XOD测定法中无活性。这些发现表明，叶片提取物的生物活性与GA和TPC有关。除XOD测定法外，GA和TPC与抗氧化和抗炎活性密切相关。该数据集突出了叶片作为抗氧化剂和抗炎特性的天然来源在制药和营养保健品应用中的潜在饮食益处。