Interdisciplinary Center Smell and Taste, Department of Otorhinolaryngology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Institute of Psychology, University of Wrocław, Wrocław, Poland.
ORL J Otorhinolaryngol Relat Spec. 2024;86(1):13-15. doi: 10.1159/000533629. Epub 2023 Oct 16.
Here, we refer to our publication "Symptoms of depression change with olfactory function" [Sci Rep. 2022 Apr 5;12(1):5656].
Depression decreases with olfactory improvement, but the question remains open of whether patients who indicate more suffering regarding mood impairment exhibit a different pattern of recovery from olfactory loss compared to those who suffer less.
In the course of an additional investigation of our previously published dataset, we established groups of participants (N = 171) with low (≤8 points on a depression [ADSL] scale; 47%; n = 45) and high (≥14 points on ADSL scale; 53%; n = 53) mood impairment.
We found that the group that reported more sufferance on a depression [ADSL] scale improved more in change of olfactory function, and, more importantly, odor discrimination change over a period of an average of 11 months.
Patients, who suffered more, as indicated by higher scores on ADSL scale, may have been more willing to commit to the study protocol, and thus their improvement was more notable.
在这里，我们提到了我们的出版物“抑郁症状随嗅觉功能变化”[Sci Rep. 2022 年 4 月 5 日；12(1):5656]。
随着嗅觉的改善，抑郁程度会降低，但仍存在一个问题，即与那些症状较轻的患者相比，那些报告情绪障碍症状更严重的患者，其嗅觉丧失的恢复模式是否不同。
在对我们之前发表的数据集进行的一项额外调查中，我们根据抑郁（ADSL）量表上的评分（≤8 分；47%；n = 45）和高（≥14 分；53%；n = 53）建立了两组参与者。
我们发现，在抑郁[ADSL]量表上报告更多痛苦的组在嗅觉功能变化方面的改善更大，更重要的是，在平均 11 个月的时间内，气味辨别能力的变化更大。
根据 ADSL 量表上的评分，那些报告症状更严重的患者可能更愿意遵守研究方案，因此他们的改善更为明显。
