Roggenkamp H G, Jung F, Nüttgens H P, Kiesewetter H, Ringelstein E B, Schneider R
Klin Wochenschr. 1986 Oct 15;64(20):1091-6.
The normal values for erythrocyte rigidity as measured by the "Selective Erythrocyte Rigidometer" were derived from a group of 275 apparently healthy subjects without risk factors. These individuals were randomly selected from an address book. The normal values ranged from 0.83-1.19 (median: 1.01). Quality control was conducted throughout the study and the analytical reliability was verified (day-to-day coefficient of variation VCd was 7.5%; coefficient of variation in series VCs was 3.1%). Inter- and intraindividual fluctuations in erythrocyte rigidity in the 8.3% and 6.1% ranges respectively were found in 20 apparently healthy subjects in the course of a 6-month study. No relationship was found between either age or sex and erythrocyte rigidity. Significantly higher erythrocyte rigidity values were found in patients with risk factors however; this applies to hypertensive patients, patients with diabetes mellitus, but also to apparently healthy subjects who were either overweight or smokers. Patients with disordered lipometabolisms on the other hand did not show any change in erythrocyte deformability when compared with healthy subjects.
通过“选择性红细胞硬度计”测量的红细胞硬度正常值来自一组275名无危险因素的明显健康受试者。这些个体是从一本通讯录中随机挑选出来的。正常值范围为0.83 - 1.19（中位数：1.01）。在整个研究过程中进行了质量控制，并验证了分析可靠性（日常变异系数VCd为7.5%；系列变异系数VCs为3.1%）。在一项为期6个月的研究过程中，在20名明显健康的受试者中分别发现红细胞硬度的个体间和个体内波动范围为8.3%和6.1%。未发现年龄或性别与红细胞硬度之间存在关联。然而，在有危险因素的患者中发现红细胞硬度值明显更高；这适用于高血压患者、糖尿病患者，也适用于超重或吸烟的明显健康受试者。另一方面，与健康受试者相比，脂质代谢紊乱患者的红细胞变形性没有任何变化。
