Craveri A, Tornaghi G, Paganardi L, Ranieri R, Di Bella M, Gallo E
Minerva Med. 1987 Jul 15;78(13):893-8.
Cigarette smoking, hypercholesterolaemia, hypertriglyceridaemia, are all known risk factors for atherosclerotic vascular lesions. Often they are associated with alterations mainly due to increased haematocrit (smoking) or to the influence of triglycerides and cholesterol on the erythrocyte membrane or plasma viscosity. In order to eliminate these factors, washed red blood cells, poor in leucocytes and platelets, in a suspension with phosphate saline buffer were studied. 20 heavy smokers, 40 patients with hyperlipidaemia (26 II a or b; 14 IV) and 50 healthy people were considered. Red blood cell viscosity was calculated at 4 shear rate between 0.37 and 69.5 sec-1. Red blood cell deformability, as an indicator of cell filtration through Nucleopore membranes was also studied. There was no difference in the filtration index among the subjects under study. Red blood cell viscosity increased in smokers and in patients with hyperlipidaemia.
吸烟、高胆固醇血症、高甘油三酯血症都是已知的动脉粥样硬化性血管病变的危险因素。它们通常与主要由于血细胞比容增加（吸烟）或甘油三酯和胆固醇对红细胞膜或血浆粘度的影响而导致的改变有关。为了消除这些因素，研究了在磷酸盐缓冲盐溶液悬浮液中白细胞和血小板含量低的洗涤红细胞。研究对象包括20名重度吸烟者、40名高脂血症患者（26例II a或b型；14例IV型）和50名健康人。在0.37至69.5秒-1之间的4个剪切速率下计算红细胞粘度。还研究了红细胞变形性，作为细胞通过核孔膜过滤的指标。在研究对象中，过滤指数没有差异。吸烟者和高脂血症患者的红细胞粘度增加。
