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与眼内压升高相关的风险因素:孟加拉国一个农村社区的基于人群的研究。

Risk factors associated with elevated intraocular pressure: a population-based study in a rural community of Bangladesh.

机构信息

Department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Department of Vitreo-Retina, National Institute of Ophthalmology and Hospital, Dhaka, Bangladesh.

出版信息

BMJ Open Ophthalmol. 2023 Oct;8(1). doi: 10.1136/bmjophth-2023-001386.

Abstract

OBJECTIVE

High intraocular pressure (IOP) is one of the major modifiable risk factors for glaucoma. The objective was to examine socio-demographic and clinical factors related to IOP.

METHODS AND ANALYSIS

This study was conducted among 3097 adults residing in a rural area of Bangladesh, with all participants undergoing clinical and ophthalmological evaluations. The measurement of IOP was carried out using of a rebound Tonometer called Icare pro. Multiple logistic regression analysis was employed to identify variables associated to IOP levels of 21 mm Hg or above. Adjusted OR (aOR) and 95% CI were reported.

RESULTS

This study found that, in total, 9% of the study population had high IOP in one or both eyes. Elevated IOP was significantly associated with respondents who were service holders (aOR 2.52; 95% CI 1.48 to 4.31), had a lower education level (aOR 1.55, 95% CI 1.07 to 2.23), used biomass fuel (aOR 2.00; 95% CI 1.09 to 3.67), belonged to a higher socioeconomic position (aOR 1.55, 95% CI 1.07 to 2.23) and had obesity (aOR 2.00; 95% CI 1.07 to 3.73), hypertension (aOR 1.32; 95% CI 1.01 to 1.73) or history of diabetes (aOR 2.44; 95% CI 1.67 to 3.55), after adjusting for covariates including age, sex, marital status, light source and tobacco consumption, in a multiple regression analysis.

CONCLUSION

Chronic diseases, such as hypertension and diabetes, obesity and sociodemographic characteristics such as high socioeconomic status and use of biomass fuels, have all been linked to elevated IOP. Patients with chronic diseases should undergo for IOP testing regularly.

摘要

目的

高眼压(IOP)是青光眼的主要可调节风险因素之一。本研究旨在探讨与 IOP 相关的社会人口学和临床因素。

方法和分析

本研究在孟加拉国农村地区对 3097 名成年人进行了研究,所有参与者均接受了临床和眼科评估。使用回弹眼压计(Icare pro)测量 IOP。采用多因素 logistic 回归分析确定与 IOP 水平为 21mmHg 或以上相关的变量。报告调整后的比值比(aOR)和 95%置信区间(CI)。

结果

本研究发现,研究人群中共有 9%的人双眼或单眼存在高眼压。与高眼压显著相关的因素包括:服务人员(aOR 2.52;95%CI 1.48 至 4.31)、教育程度较低(aOR 1.55,95%CI 1.07 至 2.23)、使用生物质燃料(aOR 2.00;95%CI 1.09 至 3.67)、社会经济地位较高(aOR 1.55,95%CI 1.07 至 2.23)和肥胖(aOR 2.00;95%CI 1.07 至 3.73)、高血压(aOR 1.32;95%CI 1.01 至 1.73)或糖尿病史(aOR 2.44;95%CI 1.67 至 3.55)。在调整了年龄、性别、婚姻状况、光源和烟草使用等混杂因素后,多元回归分析结果仍具有统计学意义。

结论

慢性疾病(如高血压和糖尿病)、肥胖以及社会人口学特征(如较高的社会经济地位和使用生物质燃料)均与眼压升高有关。患有慢性疾病的患者应定期进行 IOP 检测。

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