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孟加拉国成年人群体中失明的患病率及其决定因素:一项全国性横断面调查的结果。

Prevalence of blindness and its determinants in Bangladeshi adult population: results from a national cross-sectional survey.

机构信息

Community Ophtalmology, National Institute of Ophthalmology, Dhaka, Bangladesh.

Ophthalmology, Dhaka Medical College, Dhaka, Bangladesh.

出版信息

BMJ Open. 2022 Apr 1;12(4):e052247. doi: 10.1136/bmjopen-2021-052247.

Abstract

OBJECTIVE

The objective of this study was to determine the prevalence of blindness and its determinants in Bangladeshi adult population.

STUDY DESIGN

A cross-sectional population-based survey conducted at household level with national representation. Samples were drawn from the 2011 national census frame using a multistage stratified cluster sampling method.

SETTING AND PARTICIPANTS

The survey was done in urban and rural areas in 2013 using a probability proportionate to size sampling approach to locate participants from 72 primary sampling units. One man or one woman aged ≥40 years was randomly selected from their households to recruit 7200. In addition to sociodemographic data, information on medication for hypertension and diabetes was obtained. Blood pressure and capillary blood glucose were measured. Eyelids, cornea, lens, and retina were examined in addition to visual acuity and refraction testing.

PRIMARY OUTCOME MEASURES

The following definition was used to categorise subjects having (1) blindness: visual acuity <3/60, (2) low vision: ≥3/60 to <6/60 and (3) normal vision: ≥6/12 after best correction.

RESULTS

We could recruit 6391 (88.8%) people among whom 2955 (46.2%) were men. Among them, 1922 (30.1%) were from urban and 4469 (69.9%) were from rural areas. The mean age was 54.3 (SD 11.2) years. The age-standardised prevalence, after best correction, of blindness and low vision was 1.0% (95% CI 0.5% to 1.4%) and 12.1% (95% CI 10.5% to 13.8%), respectively. Multivariable logistic regression indicated that cataract, age-related macular degeneration and diabetic retinopathy were significantly associated with low vision and blindness after adjustment for age and sex. Population attributable risk of cataract for low vision and blindness was 79.6%.

CONCLUSIONS

Low vision and blindness are common problems in those aged 40 years or older. Extensive screening and eye care services are necessary for wider coverage engaging all tiers of the healthcare system especially focusing on cataract.

摘要

目的

本研究旨在确定孟加拉国成年人群体中的失明患病率及其决定因素。

研究设计

这是一项在家庭层面进行的具有全国代表性的横断面人群调查。使用多阶段分层聚类抽样方法,从 2011 年全国人口普查框架中抽取样本。

研究地点和参与者

该调查于 2013 年在城乡地区进行,采用概率比例大小抽样方法从 72 个初级抽样单位中定位参与者。从他们的家庭中随机选择一名 40 岁或以上的男性或女性,以招募 7200 人。除社会人口统计学数据外,还获得了高血压和糖尿病药物治疗信息。测量血压和毛细血管血糖,除视力和屈光度测试外,还检查眼睑、角膜、晶状体和视网膜。

主要观察指标

以下定义用于对以下人群进行分类:(1) 失明:视力<3/60,(2) 低视力:≥3/60 至<6/60,(3) 正常视力:经最佳矫正后≥6/12。

结果

我们可以招募到 6391 名(88.8%)参与者,其中 2955 名(46.2%)为男性。其中,1922 名(30.1%)来自城市,4469 名(69.9%)来自农村。平均年龄为 54.3(SD 11.2)岁。最佳矫正后,失明和低视力的年龄标准化患病率分别为 1.0%(95%CI 0.5%至 1.4%)和 12.1%(95%CI 10.5%至 13.8%)。多变量逻辑回归表明,白内障、年龄相关性黄斑变性和糖尿病性视网膜病变与低视力和失明在调整年龄和性别后显著相关。白内障对低视力和失明的人群归因风险为 79.6%。

结论

40 岁或以上人群中低视力和失明是常见问题。广泛的筛查和眼保健服务对于更广泛的覆盖范围是必要的,涉及所有医疗保健系统层次,特别是重点关注白内障。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ed6/8977819/aecdf14fe283/bmjopen-2021-052247f01.jpg

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