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由乳清蛋白共价修饰羧甲基纤维素稳定的高内相比乳液:增强环境稳定性、储存稳定性和生物可及性。

High internal phase emulsions stabilized by whey protein covalently modified with carboxymethyl cellulose: Enhanced environmental stability, storage stability and bioaccessibility.

机构信息

College of Forestry, Northeast Forestry University, Harbin 150040, China.

College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, China.

出版信息

Food Chem. 2024 Mar 15;436:137634. doi: 10.1016/j.foodchem.2023.137634. Epub 2023 Oct 5.

DOI:10.1016/j.foodchem.2023.137634
PMID:37847963
Abstract

In this work, the effects of whey protein-carboxymethyl cellulose (WP-CMC) conjugates on the environmental stability, in vitro digestion stability, storage stability and bioaccessibility of high internal phase emulsions (HIPEs) were investigated. Compared to the HIPEs stabilized by the mixture of WP and CMC, the HIPEs stabilized by WP-CMC were less sensitive to environmental changes by particle size and zeta-potential, and showed better stability and bioavailability of pine nut oil as well as β-carotene during simulated gastrointestinal digestion. In addition, the inclusion function and pine nut oil oxidative stability of the HIPEs stabilized by WP-CMC were better during 16 days of storage than those of the pine nut oil and HIPEs stabilized by the mixture of WP and CMC, and also expressed higher storage stability of β-carotene. These results suggested that the conjugate-stabilized emulsions developed in this study have potential applications as protectors and carriers of liposoluble active ingredients.

摘要

在这项工作中,研究了乳清蛋白-羧甲基纤维素(WP-CMC)缀合物对高内相乳液(HIPE)的环境稳定性、体外消化稳定性、储存稳定性和生物利用度的影响。与由 WP 和 CMC 的混合物稳定的 HIPE 相比,由 WP-CMC 稳定的 HIPE 对粒径和 ζ 电位的环境变化的敏感性较低,并且在模拟胃肠道消化过程中表现出更好的稳定性和生物可及性,以及更好的松子油和 β-胡萝卜素的生物利用度。此外,在 16 天的储存期内,由 WP-CMC 稳定的 HIPE 的包埋功能和松子油的氧化稳定性优于由 WP 和 CMC 的混合物稳定的松子油和 HIPE,并且还表现出更高的 β-胡萝卜素的储存稳定性。这些结果表明,本研究中开发的缀合物稳定的乳液具有作为脂溶性活性成分的保护剂和载体的潜力。

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