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一名未控制的糖尿病患者的广泛性死骨形成慢性上颌骨骨髓炎:一种罕见病症的综合病例管理

Extensive Sequestration Chronic Maxillary Osteomyelitis in an Uncontrolled Diabetic Patient: Comprehensive Case Management of a Rare Entity.

作者信息

El Fadhlallah Prasiddha Mahardhika, Nugraha Andreas Pratama, Prasetio Okky, Mulyawan Indra

机构信息

Oral and Maxillofacial Surgery Specialist Program, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.

Department of Oral and Maxillofacial Surgery, Dr Mohamad Soewandhie General Hospital, Surabaya, Indonesia.

出版信息

Eur J Dent. 2024 Feb;18(1):401-407. doi: 10.1055/s-0043-1771536. Epub 2023 Oct 17.

Abstract

The hallmark of osteomyelitis was progressive bone destruction and sequestrum formation. In the underlying disease, like diabetes mellitus, osteomyelitis becomes severe and exacerbates the condition. It was essential for the oral and maxillofacial surgeon to comprehend its complex medical and surgical management to achieve complete disease eradication. The aim of this article was to report a rare case and comprehensive management of extensive sequestrating maxillary osteomyelitis with uncontrolled diabetes mellitus patients. A 58-year-old male patient with pain and swelling accompanied by discharge of pus in the sinistra maxilla region. The systemic disease was identified as uncontrolled diabetes mellitus, and had a history of unhealing wounds 1 year ago after upper left molar extraction. Computed tomography scan result showed extensive sequester formation and bony destruction in the right extending to the left maxilla. Microbial culture results were and Subsequently, extensive sequestrectomy and multiple extractions of the involved jaw and teeth were performed after diabetes mellitus was regulated. A suspension suture against oral and nasal mucosa was performed to avoid dead space formation. Comprehensive perioperative management in maxillary osteomyelitis in uncontrolled diabetes mellitus includes sequestrectomy, definitive antibiotic therapy based on culture results, and diabetes regulation to improve the successful management of this case.

摘要

骨髓炎的标志是进行性骨破坏和死骨形成。在诸如糖尿病等基础疾病中,骨髓炎会变得严重并加重病情。口腔颌面外科医生必须了解其复杂的内科和外科治疗方法,以实现疾病的彻底根除。本文的目的是报告1例患有未控制的糖尿病的广泛性上颌骨骨髓炎伴死骨形成患者的罕见病例及综合治疗情况。一名58岁男性患者,左侧上颌骨区域疼痛、肿胀并伴有脓性分泌物。全身疾病被诊断为未控制的糖尿病,患者有1年前左上磨牙拔除后伤口不愈合的病史。计算机断层扫描结果显示右侧广泛形成死骨并伴有骨质破坏,病变延伸至左侧上颌骨。微生物培养结果为……随后,在糖尿病得到控制后,进行了广泛的死骨切除术以及受累颌骨和牙齿的多次拔除。进行了口腔黏膜与鼻黏膜的悬吊缝合以避免死腔形成。对患有未控制的糖尿病的上颌骨骨髓炎患者进行综合围手术期管理包括死骨切除术、根据培养结果进行明确的抗生素治疗以及控制糖尿病,以提高该病例的治疗成功率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99ec/10959603/0458098dd0d9/10-1055-s-0043-1771536-i2322709-1.jpg

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